DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gos28 and gos-28

DIOPT Version :9

Sequence 1:	NP_650739.2	Gene:	Gos28 / 248102	FlyBaseID:	FBgn0044871	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_498621.1	Gene:	gos-28 / 176044	WormBaseID:	WBGene00017273	Length:	234	Species:	Caenorhabditis elegans

Alignment Length:	241	Identity:	83/241 - (34%)
Similarity:	144/241 - (59%)	Gaps:	23/241 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SYDVLRKQARSLENEIDLKLVAFSKIGAGSGGGGSGGLGGVDTSPLLGEHV-FDSLSEEIEQMLE 68
            :::.|||:|||.||.||:|||:.:|:.|.|.||..     :|...:..... |.:::.|||.::|
Worm     4 TWEALRKKARSTENSIDVKLVSLNKLTASSHGGFD-----IDEKTVSSRQTSFKTVTTEIEGLIE 63

  Fly    69 KLSSLNESMSDLP--------ASGAAAMHTLQRHREILQGYRQEFNKICANHTMRIEREELLRGS 125
            :|:::|:.|:|:.        |:..|..|||:||||||:.|..|:.:...|....::||.||..|
Worm    64 QLTNINDDMNDVAGAQSSASWANNPAIQHTLRRHREILRDYGSEYRRARDNVDQVLQRELLLSSS 128

  Fly   126 GLATSSGSPSISGLNRR----EMYLKESGHLNSASHLVNDQINIAIETRDHLHAQRQAFKRLQTR 186
            .  .:..:|.   ||.|    :|||||:.|:|:...|:::|:.:|:.|::::..|....:.:.||
Worm   129 N--ENRNNPI---LNNRARGYDMYLKENDHINACDRLLDEQLEMAMSTKENMARQGINLRGISTR 188

  Fly   187 FNDISNRFPLISSLIQRINIKKRRDSLILGAVIGFCVILLLLYAFN 232
            .:.||.::|.|::|:|:|..||::::|||.|||..|:|..:.:..|
Worm   189 LHHISKKYPAINNLMQKIKTKKQKNTLILAAVISSCLIFTIFWIIN 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gos28	NP_650739.2	SNARE	142..207	CDD:419871	22/68 (32%)
gos-28	NP_498621.1	SNARE	145..206	CDD:304603	20/60 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157490
Domainoid	1	1.000	78	1.000	Domainoid score	I5718
eggNOG	1	0.900	-	-		E1_KOG3208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37977
Inparanoid	1	1.050	142	1.000	Inparanoid score	I3062
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55290
OrthoDB	1	1.010	-	-		D1319902at2759
OrthoFinder	1	1.000	-	-		FOG0004151
OrthoInspector	1	1.000	-	-		oto20203
orthoMCL	1	0.900	-	-		OOG6_102989
Panther	1	1.100	-	-	LDO	PTHR21094
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R505
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800