DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gos28 and gosr1

DIOPT Version :9

Sequence 1:	NP_650739.2	Gene:	Gos28 / 248102	FlyBaseID:	FBgn0044871	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	XP_005157622.1	Gene:	gosr1 / 100001316	ZFINID:	ZDB-GENE-050417-133	Length:	248	Species:	Danio rerio

Alignment Length:	247	Identity:	120/247 - (48%)
Similarity:	167/247 - (67%)	Gaps:	17/247 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GGSS--YDVLRKQARSLENEIDLKLVAFSKI--GAGSGGGGSGGLGGVDTSPLL----GEHVFDS 58
            ||:|  ::.||||||.||||:|||||:|||:  ...|...|..|....||:|||    .:.:|::
Zfish     3 GGNSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSSSRDGRRGDSSSDTTPLLCNSTQDRMFET 67

  Fly    59 LSEEIEQMLEKLSSLNESMSDLPAS------GAAAMHTLQRHREILQGYRQEFNKICANHTMRIE 117
            :|.||||:|.||:.:|:.|::..::      .||.||||||||:|||.|..||:|..:|.....|
Zfish    68 MSVEIEQLLAKLTGVNDKMAEYTSTPGVTSLNAALMHTLQRHRDILQDYTHEFHKTKSNFMAIRE 132

  Fly   118 REELLRGSGLATSSGSPSISGLNRR--EMYLKESGHLNSASHLVNDQINIAIETRDHLHAQRQAF 180
            ||:|| ||.........|.||:|.|  |::|||..||.::..|::|.|:||:.|::::.:||...
Zfish   133 REDLL-GSVRKDIETYKSGSGVNNRRTELFLKEHEHLRNSDRLIDDTISIAMATKENMTSQRGLL 196

  Fly   181 KRLQTRFNDISNRFPLISSLIQRINIKKRRDSLILGAVIGFCVILLLLYAFN 232
            |.:|:|.|.::||||.|::||||||::|||||||||.|||.|.||||||||:
Zfish   197 KSIQSRVNTLANRFPAINNLIQRINLRKRRDSLILGGVIGICTILLLLYAFH 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gos28	NP_650739.2	SNARE	142..207	CDD:419871	30/66 (45%)
gosr1	XP_005157622.1	SNARE_GS28	158..223	CDD:277217	29/64 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576008
Domainoid	1	1.000	102	1.000	Domainoid score	I6832
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37977
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3739
OMA	1	1.010	-	-		QHG55290
OrthoDB	1	1.010	-	-		D1319902at2759
OrthoFinder	1	1.000	-	-		FOG0004151
OrthoInspector	1	1.000	-	-		oto38851
orthoMCL	1	0.900	-	-		OOG6_102989
Panther	1	1.100	-	-	LDO	PTHR21094
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R505
SonicParanoid	1	1.000	-	-		X5179
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.900