Protein Alignment Slc5a2 and CG33124

DIOPT Version :9

• Sequence 1: NP_573517.1
• Gene: Slc5a2 / 246787
• MGIID: 2181411
• Length: 670
• Species: Mus musculus
• Sequence 2: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 139/633 - (21%)
• Similarity: 254/633 - (40%)
• Gaps: 142/633 - (22%)

Mouse    23 DILVIAAYFLLVIGVGLW-------------------SMFRTNRGT--VGGYFLAGRSMVWWPVG 66
            |..|.....:|.|.:||:                   .:...|.|:  :..|.:....:..:||.
  Fly    10 DYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFPVA 74

Mouse    67 ASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLL-----GWLFVPVYLTAGVITMPQY 126
            .||.||.|.     |:|..|..|.:...|.:::.:.:.:::     .::::||:....|.:..:|
  Fly    75 MSLIASFIS-----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEY 134

Mouse   127 LRKRFGGH-RIRLYLSVLSLF-LYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVT 189
            |..||  | .||..:|::.:. :.::|...|  |..|:.:.||.|.||:...:.::.:.:|||:.
  Fly   135 LGMRF--HPLIRNIVSIMFVIEVLLYTPFVV--FVPALALNQASGLNIHMIEVLIIVVCVIYTLL 195

Mouse   190 GGLAALMYTDTVQTFVILAGAFILTGYAFHEVGGYSGLFDKYLGAMTSLTVSKDPSVGNISSTCY 254
            |||.|:::||..|..::.|...::...|...:......|:       ||........|||:.:.|
  Fly   196 GGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFE-------SLVDGGRLIFGNINPSPY 253

Mouse   255 QPRPDSYHLLRDPVTGDLPWPALLLGLTIVSGWYWCS----DQVIVQRCLAGKNLTHIKAGC--I 313
                     :|:.|     |..::.|     .:||.|    .|.:|.|.::..||...:...  .
  Fly   254 ---------VRNTV-----WSVVIGG-----AFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFF 299

Mouse   314 LCGYLKLMPMFLMVMP--GMISRILYPDEVACVVPEVCKRVCGTEVGCSNIAYPRLVVKLMPN-- 374
            :.|.:    :|..|:.  |::...:|.|         |..:...::..::...|..||:.:.:
  Fly   300 VLGSI----IFYSVLSFLGLLIFNMYKD---------CDPLSAGQIMNNDQLVPLFVVQSVGHIY 351

Mouse   375 GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYT---RLRPRAGDKELLLVGRLWVVFIVAVSV 436
            |:.||.:|.:..|.:|||:...||:|.:...||..   :::|  |:....::.:..:|.:.|:..
  Fly   352 GIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQP--GETASAIIVKATIVIMGALVF 414

Mouse   437 AWLPVVQAAQGGQLFDYIQSVSSYLAPPVSAVFVLALFVPRVNEKG-AFWGLVGGLLMGLARLIP 500
            ..:.:::...|  :.....|:.:........:|.||:.||..|..| |..|:.|.||.|......
  Fly   415 GEVLLLEKVSG--ILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVGGIAGFLLTGWITFGS 477

Mouse   501 EFFFGSGSC------VRPSACPA-----------------LFCRVHYLYFAIILFICSGILTLG- 541
            :....||..      |..::||.                 || |:.:.:...|     |.||:.
  Fly   478 QIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLF-RLSFHWINPI-----GALTVVV 536

Mouse   542 ----ISLCTAPIPQKHL---------HRLV----FSLRH-SKEEREDL 571
                :||.|.|...|.|         ||.:    |..|: .|.|..|:
  Fly   537 VGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRNLDKSEATDI 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a2	NP_573517.1	SLC5-6-like_sbd	22..670	CDD:294310	139/633 (22%)
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	124/580 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750