DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG46385 and tent5bb

DIOPT Version :9

Sequence 1:	NP_001356959.1	Gene:	CG46385 / 246653	FlyBaseID:	FBgn0286778	Length:	1107	Species:	Drosophila melanogaster
Sequence 2:	NP_001038635.1	Gene:	tent5bb / 568893	ZFINID:	ZDB-GENE-060503-431	Length:	393	Species:	Danio rerio

Alignment Length:	341	Identity:	202/341 - (59%)
Similarity:	252/341 - (73%)	Gaps:	12/341 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 QRLAVLSFEQVSKLHDVMDEKVAIHGRGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGVLVKDIR 459
            :|..|||:|||.:|..::.|.|.||||||||||.|:.:.:|.:||.:||..      ||.|:|::
Zfish    11 RRCCVLSWEQVQRLDSILGECVPIHGRGNFPTLSVQPRHIVQVVRARLEER------GVKVRDVK 69

  Fly   460 LNGGAASHVLASE-DQPYNDLDLIFAIELSSPRVFDRVKVAVLNTLLDLMPEGVCKRRIYTCSLK 523
            |||.|||:||..: ...|.||||||.:.|:..:.|..||..||:.||:.:|.||.:.||...:||
Zfish    70 LNGSAASYVLHQDTGLGYKDLDLIFGLSLTDDKTFRLVKDVVLDCLLEFLPAGVSRDRITALTLK 134

  Fly   524 EAYVGKMVKVNNNNDGDRWSLISLGNSPGHKNVELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDC 588
            ||||.|:|||  .||.||||||||.|:.| |||||||||::|||||||||||||.|||||||..|
Zfish   135 EAYVQKLVKV--CNDTDRWSLISLSNNTG-KNVELKFVDSLRRQFEFSVDSFQIGLDSLLLFDRC 196

  Fly   589 AALPISENFYPTVVGESVYGDFQEALYHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYKAVDSQL 653
            :..|:||:|:|||:|||:||||:|||.||..|:|:|..|||||||||||||:||||.::......
Zfish   197 SETPMSESFHPTVLGESMYGDFEEALGHLHAKIIATHSPEEIRGGGLLKYCHLLVRGFRPASEAQ 261

  Fly   654 IKTLERYMCSRFFIDFPDINTQTTKLEAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTVCLMGHE 718
            :|||:|||||||||||.|||.|..||||||:|||.|::.:  :|..|:.|..||:.|||||||||
Zfish   262 MKTLQRYMCSRFFIDFSDINEQQRKLEAYLQNHFNGMEHK--RYDCLVTLHRVVDESTVCLMGHE 324

  Fly   719 RRQSLHLIQSLAAQVL 734
            |||:|.||.|||.:||
Zfish   325 RRQTLALISSLALRVL 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG46385	NP_001356959.1	NTP_transf_7	400..727	CDD:311785	194/327 (59%)
tent5bb	NP_001038635.1	NTP_transf_7	16..333	CDD:285258	194/327 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573307
Domainoid	1	1.000	388	1.000	Domainoid score	I759
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000843
OrthoInspector	1	1.000	-	-		otm24679
orthoMCL	1	0.900	-	-		OOG6_104729
Panther	1	1.100	-	-	O	PTHR12974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X528
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.840