DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG46385 and Tent5b

DIOPT Version :9

Sequence 1:	NP_001356959.1	Gene:	CG46385 / 246653	FlyBaseID:	FBgn0286778	Length:	1107	Species:	Drosophila melanogaster
Sequence 2:	NP_001101377.1	Gene:	Tent5b / 313019	RGDID:	1308967	Length:	427	Species:	Rattus norvegicus

Alignment Length:	380	Identity:	199/380 - (52%)
Similarity:	248/380 - (65%)	Gaps:	16/380 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   361 DGGTETPPPSPSSG--SSIASTSDHG---SLESVDTGGTQRLAVLSFEQVSKLHDVMDEKVAIHG 420
            |...|.|.....:|  |::|:....|   .||:......:..:.||:.||.:|..::.|.:.|||
  Rat     8 DESLEQPAAQVGTGAASAVATAGAAGGGPDLEASSASLGRHQSRLSWPQVKRLDALLKEPIPIHG 72

  Fly   421 RGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGVLVKDIRLNGGAASHVLASED-QPYNDLDLIFA 484
            |||||||.|:.:.:|.:||..||.:      |:.|..:||:|.||||||..|. ..|.||||:|.
  Rat    73 RGNFPTLSVQPQQIVQVVRSSLEEQ------GLHVHSVRLHGSAASHVLHPESGLGYKDLDLVFQ 131

  Fly   485 IELSSPRVFDRVKVAVLNTLLDLMPEGVCKRRIYTCSLKEAYVGKMVKVNNNNDGDRWSLISLGN 549
            ::|.|...|...|..||..|||.:|.||.:.:|...:||||||.|:|||  ..|.||||||||.|
  Rat   132 MDLQSEASFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKV--CTDLDRWSLISLSN 194

  Fly   550 SPGHKNVELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDCAALPISENFYPTVVGESVYGDFQEAL 614
            ..| |||||||||::|||||||:|||||:|||||||..|::.|:||.|:|||.|||:||||.|||
  Rat   195 KSG-KNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFAEAL 258

  Fly   615 YHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYKAVDSQLIKTLERYMCSRFFIDFPDINTQTTKL 679
            .|||.::|:||.|||||||||||||:||||.::...|..::.|:|||||||||||||...|...|
  Rat   259 EHLQHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDPVEQRRIL 323

  Fly   680 EAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTVCLMGHERRQSLHLIQSLAAQVL 734
            |.||..||.|. |...:|..|:.|..||..||||||.|||||:|.||..||.|.|
  Rat   324 ERYLEAHFGGA-EAARRYACLVTLHRVVNESTVCLMSHERRQTLDLITMLALQAL 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG46385	NP_001356959.1	NTP_transf_7	400..727	CDD:311785	185/327 (57%)
Tent5b	NP_001101377.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46		9/37 (24%)
Tent5b	NP_001101377.1	NTP_transf_7	52..371	CDD:285258	186/328 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334311
Domainoid	1	1.000	387	1.000	Domainoid score	I769
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000843
OrthoInspector	1	1.000	-	-		otm44797
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12974
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X528
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.940