Protein Alignment CG30496 and GLMN

DIOPT Version :10

• Sequence 1: NP_724595.1
• Gene: CG30496 / 246652
• FlyBaseID: FBgn0050496
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_016855626.1
• Gene: GLMN / 11146
• HGNCID: 14373
• Length: 627
• Species: Homo sapiens
• Alignment Length: 657
• Identity: 161/657 - (24%)
• Similarity: 294/657 - (44%)
• Gaps: 128/657 - (19%)

  Fly     1 MQEQEMEVEVGDPAKASNLLRLIKQLLLEKAY-DGVRMLFQSAQESEKNTRLLPHIAMDLYHDV- 63
            ::||:.:.|      ...|.:|..|..:|:.: |.:..:.|    :|||..::.::..:|...|
Human    49 LEEQDFKEE------DFGLFQLAGQRCIEEGHTDQLLEIIQ----NEKNKVIIKNMGWNLVGPVV 103

  Fly    64 -CLENISDEVNSQEPELFDCSDELLKLLAKYAPLHELMLELMERLEESSSINVFGA---YLRALQ 124
             || ...|:.:|:....|...|    ||.|.....||:|.|:|.:||.|...:..:   .|:.||
Human   104 RCL-LCKDKEDSKRKVYFLIFD----LLVKLCNPKELLLGLLELIEEPSGKQISQSILLLLQPLQ 163

  Fly   125 VVLQRQGRDKPQAVEWSLNSIFTHLKDLPLPEYLSE-------GYDEAQARLIEQNEQ-VEDLLA 181
            .|:|:. .:|..::..:|::::..|..||:| |..|       |..:....|||..:. ||:::.
Human   164 TVIQKL-HNKAYSIGLALSTLWNQLSLLPVP-YSKEQIQMDDYGLCQCCKALIEFTKPFVEEVID 226

  Fly   182 HYITVGLFREPLRDEILQ---QDVRTP---SQIFRDCGVNRRNIFTCF------FIQLLGRPLAL 234
            :... .|..|.|:||:|:   :.::.|   :|.|........:.|..|      |:..:|.|...
Human   227 NKEN-SLENEKLKDELLKFCFKSLKCPLLTAQFFEQSEEGGNDPFRYFASEIIGFLSAIGHPFPK 290

  Fly   235 LEMNHAKEDLTRSYVQQVTESLTQDANQFLGDPFYLLNLVEQRARWLRKLDASRGVYEMSCQNVF 299
            :..||.::..|.:|::     ..::.|:.|.|....|                  .|.:..|.:.
Human   291 MIFNHGRKKRTWNYLE-----FEEEENKQLADSMASL------------------AYLVFVQGIH 332

  Fly   300 LIEEKLPLHAVAMYYHSLFVGNQLPTNAPKVYAPLFLFETIVYLAEVLLRQQEPPLQYCGLRLVE 364
            :                    :||    |.|.:||:|.:..:...||.|::.|..:...||.|:|
Human   333 I--------------------DQL----PMVLSPLYLLQFNMGHIEVFLQRTEESVISKGLELLE 373

  Fly   365 HHLSTLQ-HSVPTSSLQLDVHKRFCEALCKIVGYSPQVALRQLGIHVLRQFVLAFDDHGKYLILK 428
            :.|..:: :|:....|::.......:.|.|::...|...||:..:.:|:.::...|..|||.:.:
Human   374 NSLLRIEDNSLLYQYLEIKSFLTVPQGLVKVMTLCPIETLRKKSLAMLQLYINKLDSQGKYTLFR 438

  Fly   429 NLMGTLQHGGLMGYLGGMYKDLVDKALGQ-------SGPMPEVYSGKLFREMLLLCVCVLPHDVK 486
            .|:.|..|.|:..::....|:.:|.:|.:       :|  |::.|       ||..|..||...:
Human   439 CLLNTSNHSGVEAFIIQNIKNQIDMSLKRTRNNKWFTG--PQLIS-------LLDLVLFLPEGAE 494

  Fly   487 SDLLLHSDRLCHALNILRYFAARD-KND-VTGFWQALPEIEKELLDPLGTALNFSMAHYKAYKER 549
            :|||.:|||:..:||:|||...:| :|| .||.|..|..||...|.||...||.|.|||:|   .
Human   495 TDLLQNSDRIMASLNLLRYLVIKDNENDNQTGLWTELGNIENNFLKPLHIGLNMSKAHYEA---E 556

  Fly   550 VEKGQSASDDELMQRQLNMLAVNISNSGMAGGDAESKLPDIGRQEKLDVLASSITSLETLQSLYL 614
            ::..|.|      |:..::.::.:|.         .::|::..:.:|.||.|::.:.:.::|:..
Human   557 IKNSQEA------QKSKDLCSITVSG---------EEIPNMPPEMQLKVLHSALFTFDLIESVLA 606

  Fly   615 RAREIIE 621
            |..|:||
Human   607 RVEELIE 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30496	NP_724595.1	Kinetochor_Ybp2	2..548	CDD:400745	147/581 (25%)
GLMN	XP_016855626.1	Kinetochor_Ybp2	34..563	CDD:400745	148/590 (25%)