DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30495 and si:dkey-174n20.1

DIOPT Version :9

Sequence 1:	NP_001260785.1	Gene:	CG30495 / 246651	FlyBaseID:	FBgn0050495	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	XP_005165244.1	Gene:	si:dkey-174n20.1 / 796174	ZFINID:	ZDB-GENE-030131-7890	Length:	308	Species:	Danio rerio

Alignment Length:	325	Identity:	125/325 - (38%)
Similarity:	193/325 - (59%)	Gaps:	25/325 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VFLAHGIV-GIIAFCVRLYMQGGKF---RKQTDETGKVAIVTGGNTGLGKETVMELARRGATVYM 74
            ::|.:.|: .::.|.|..:|:..::   .|:.|  ||..::||||:|:||||.:.||.|||.|.:
Zfish     1 MYLLYTIISALVCFLVLKWMKRRRYCTDLKRLD--GKTVLITGGNSGIGKETAVALAMRGARVII 63

  Fly    75 ACRNKEKVERARREIVKETGNSNVFSRECDLSSLDSIRKFAENFKKEQRVLHILINNAG----VF 135
            |||::||..:|.|||...:.|.||...|.||:::.|||:|::.|.::::.|.|||||||    :.
Zfish    64 ACRDEEKARKAVREIKARSHNMNVLHMEVDLANMRSIREFSKTFLQKEKRLDILINNAGMPGVLD 128

  Fly   136 WEPHRLTKEGFEMHLGVNHIGHFLLTNLLLGVLERSAPSRVVVVASRAHERGQIKVDDINSSDFY 200
            |     |.:.|.|..||||:||||||||||..|:.|:||||:.:...:::..::...|:|.:.|
Zfish   129 W-----TDDNFSMCFGVNHLGHFLLTNLLLPRLKESSPSRVINLTCSSYKYQKLNFQDLNYNLF- 187

  Fly   201 DEGVAYCQSKLANILFTRELAKRLEGTGVTVNALNPGIADTEIARNMIFFQTKFAQYVVETILRP 265
             ....||:||||||.||:|||:.:||.|||..|::||...:....:........||.|
Zfish   188 -PFFTYCRSKLANIYFTQELARMMEGKGVTAYAVHPGYVRSRWTCHFSVLYQILAQVV------- 244

  Fly   266 LLWAVMKTPKNGAQTTLYAALDPDLERVSGQYFSDCALAPVAPAALDDQMAQWLWAQSEKWAKIA 330
             ::....:.:.||||.:|.|:..::...:|.||:||..||:...|.|..:|:.||..||:..|:|
Zfish   245 -MFMFFVSCEAGAQTVVYCAVSDEVLPRNGGYFTDCRPAPLKAFARDSGVAKKLWEASERLVKLA 308

Fly 331 330
Zfish 309 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30495	NP_001260785.1	FabG	44..296	CDD:223959	102/255 (40%)
CG30495	NP_001260785.1	NADB_Rossmann	45..323	CDD:304358	114/281 (41%)
si:dkey-174n20.1	XP_005165244.1	PRK06197	28..304	CDD:235737	118/292 (40%)
si:dkey-174n20.1	XP_005165244.1	NADB_Rossmann	34..301	CDD:304358	114/281 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830