DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30495 and rdh12

DIOPT Version :9

Sequence 1:	NP_001260785.1	Gene:	CG30495 / 246651	FlyBaseID:	FBgn0050495	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001002325.1	Gene:	rdh12 / 436597	ZFINID:	ZDB-GENE-040718-9	Length:	319	Species:	Danio rerio

Alignment Length:	317	Identity:	153/317 - (48%)
Similarity:	209/317 - (65%)	Gaps:	18/317 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IAPVFLAHGIVGIIAFCVRL-------YMQGGKFRKQTDETGKVAIVTGGNTGLGKETVMELARR 68
            :|.|..|.|: |::|..:||       |..||..|......||||:|||.|:|:||||.::||.|
Zfish     2 LALVAFAAGL-GLVALILRLLSPQIRKYAAGGSCRSTVRLDGKVALVTGANSGIGKETALDLASR 65

  Fly    69 GATVYMACRNKEKVERARREIVKETGNSNVFSRECDLSSLDSIRKFAENFKKEQRVLHILINNAG 133
            ||.|.:|||:.||.|.|..||....|.:.|..||.||:...|||.||:.|.:|...|||||||||
Zfish    66 GARVILACRDLEKAEEAAAEIRTRVGGAKVEVRELDLADCCSIRAFAQRFLREVDHLHILINNAG 130

  Fly   134 VFWEPHRLTKEGFEMHLGVNHIGHFLLTNLLLGVLERSAPSRVVVVASRAHERGQIKVDDINSSD 198
            |...|:..|.:||||.:||||:||:|||.||:|:|:||||||:|||:|.||..|.|:..|::|..
Zfish   131 VMMCPYMKTADGFEMQIGVNHLGHYLLTYLLIGLLKRSAPSRIVVVSSLAHNFGWIRFHDLHSQG 195

  Fly   199 FYDEGVAYCQSKLANILFTRELAKRLEGTGVTVNALNPGIADTEIARNMIFFQTKFAQYVVETIL 263
            .|:.|:|||||||||:|||||||:||:|:.||||:::||...:|:.|:.......||.:.:
Zfish   196 SYNSGLAYCQSKLANVLFTRELARRLQGSNVTVNSVHPGTVRSELVRHSTLMSLLFAFFSM---- 256

  Fly   264 RPLLWAVMKTPKNGAQTTLYAALDPDLERVSGQYFSDCALAPVAPAALDDQMAQWLW 320
                  .:|:||.||||::|.|:..:|:.:||::|||||.|.|||....::.|:.||
Zfish   257 ------FLKSPKEGAQTSIYCAVAEELQSISGKHFSDCAPAFVAPQGRSEETARKLW 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30495	NP_001260785.1	FabG	44..296	CDD:223959	128/251 (51%)
CG30495	NP_001260785.1	NADB_Rossmann	45..323	CDD:304358	141/276 (51%)
rdh12	NP_001002325.1	PRK06197	41..318	CDD:235737	141/277 (51%)
rdh12	NP_001002325.1	NADB_Rossmann	42..310	CDD:304358	141/276 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9897
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.790