DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30495 and rdh14b

DIOPT Version :9

Sequence 1:	NP_001260785.1	Gene:	CG30495 / 246651	FlyBaseID:	FBgn0050495	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001040655.1	Gene:	rdh14b / 334665	ZFINID:	ZDB-GENE-030131-6605	Length:	323	Species:	Danio rerio

Alignment Length:	328	Identity:	144/328 - (43%)
Similarity:	201/328 - (61%)	Gaps:	29/328 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 APVFLAHGIVGIIAFCVRLYMQGGKFRKQTDE---------TGKVAIVTGGNTGLGKETVMELAR 67
            |.|.||..:.|.:.|..|..:    ||::...         .||..||||.|.|:||.|..||.:
Zfish     3 AAVVLAAVLGGGVFFIARRII----FRRKALRLMSYPPALMRGKTVIVTGANCGIGKATAAELLK 63

  Fly    68 RGATVYMACRNKEKVERARREIVKETGNS--NVFSRECDLSSLDSIRKFAENFKKEQRVLHILIN 130
            ..|.|.||||::::.|.|.|:|..:.|.|  .:..:..||:||.|:|:|.|...:|:..:.:|||
Zfish    64 LQARVIMACRDRQRAEDAARDIQNQAGTSQGEIVIKHLDLASLQSVRRFCEEVIREEPRIDVLIN 128

  Fly   131 NAGVFWEPHRLTKEGFEMHLGVNHIGHFLLTNLLLGVLERSAPSRVVVVASRAHERGQIKVDDIN 195
            |||::..|:..|:|||||.|||||:||||||||||.:|::|:|||||||:|:.::.|.|..:|:|
Zfish   129 NAGLYQCPYSKTEEGFEMQLGVNHLGHFLLTNLLLDLLKQSSPSRVVVVSSKLYKYGSINFEDLN 193

  Fly   196 SSDFYDEGVAYCQSKLANILFTRELAKRLEGTGVTVNALNPGIADTEIARNMIFFQTKFAQYVVE 260
            |...|::...|.||||||:|||||||:||:||.||||||.|||..|.:.|::          .:.
Zfish   194 SEQSYNKSFCYSQSKLANLLFTRELARRLDGTEVTVNALTPGIVRTRLGRHV----------NIP 248

  Fly   261 TILRPLLWAV----MKTPKNGAQTTLYAALDPDLERVSGQYFSDCALAPVAPAALDDQMAQWLWA 321
            .:::||.|.|    .|:|..||||.||.|..|::|.|||:.|::|....:...|.||..|:.||.
Zfish   249 LLIKPLFWLVSWLFFKSPLEGAQTPLYLACSPEVEGVSGKCFANCEEEQLLSKATDDHAAKRLWD 313

  Fly   322 QSE 324
            .||
Zfish   314 LSE 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30495	NP_001260785.1	FabG	44..296	CDD:223959	124/257 (48%)
CG30495	NP_001260785.1	NADB_Rossmann	45..323	CDD:304358	133/283 (47%)
rdh14b	NP_001040655.1	PRK06197	41..322	CDD:235737	135/286 (47%)
rdh14b	NP_001040655.1	NADB_Rossmann	41..315	CDD:304358	133/283 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.730