Protein Alignment CG30495 and Rdh12

DIOPT Version :10

• Sequence 1: NP_001260785.1
• Gene: CG30495 / 246651
• FlyBaseID: FBgn0050495
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_001101507.1
• Gene: Rdh12 / 314264
• RGDID: 1310462
• Length: 316
• Species: Rattus norvegicus
• Alignment Length: 297
• Identity: 148/297 - (49%)
• Similarity: 189/297 - (63%)
• Gaps: 18/297 - (6%)

  Fly    28 VRLYMQGGKFRKQTDETGKVAIVTGGNTGLGKETVMELARRGATVYMACRNKEKVERARREIVKE 92
            :|.:..||....:....|||.::||.|||:||||..|||||||.||:|||:..|.|.|..||..:
  Rat    22 IRKFFAGGVCTTKVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRAD 86

  Fly    93 TGNSNVFSRECDLSSLDSIRKFAENFKKEQRVLHILINNAGVFWEPHRLTKEGFEMHLGVNHIGH 157
            |.||.|..|:.|||...|||.|||.|..|::.||||||||||...|:..|.:|||.|.||||:||
  Rat    87 TKNSQVLVRKLDLSDTKSIRTFAEGFLAEEKKLHILINNAGVMMCPYSKTVDGFETHFGVNHLGH 151

  Fly   158 FLLTNLLLGVLERSAPSRVVVVASRAHERGQIKVDDINSSDFYDEGVAYCQSKLANILFTRELAK 222
            ||||.||||.|:.|||:||:.::|.||..|:|:..|:.|...|..|.||..|||||:||||||||
  Rat   152 FLLTYLLLGRLKESAPARVINLSSVAHLGGKIRFHDLQSKKRYCSGFAYSHSKLANVLFTRELAK 216

  Fly   223 RLEGTGVTVNALNPGIADTEIARNMIFFQTKFAQYVVETILRPLLWAV----MKTPKNGAQTTLY 283
            ||:|||||...::||...:||.|:              :.|..|||.:    .|:|..||||:|:
  Rat   217 RLQGTGVTAYVVHPGCVLSEITRH--------------SFLMCLLWRLFSPFFKSPWQGAQTSLH 267

  Fly   284 AALDPDLERVSGQYFSDCALAPVAPAALDDQMAQWLW 320
            .||:..||.:||:|||||....|:|.|.:.:.|:.||
  Rat   268 CALEEGLEPLSGKYFSDCKRTWVSPRARNKKTAERLW 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30495	NP_001260785.1	Rossmann-fold NAD(P)(+)-binding proteins	45..323	CDD:473865	145/280 (52%)
Rdh12	NP_001101507.1	Rossmann-fold NAD(P)(+)-binding proteins	39..307	CDD:473865	145/280 (52%)