Protein Alignment CG30495 and dhs-22

DIOPT Version :10

• Sequence 1: NP_001260785.1
• Gene: CG30495 / 246651
• FlyBaseID: FBgn0050495
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_506570.1
• Gene: dhs-22 / 179940
• WormBaseID: WBGene00000985
• Length: 333
• Species: Caenorhabditis elegans
• Alignment Length: 318
• Identity: 129/318 - (40%)
• Similarity: 189/318 - (59%)
• Gaps: 19/318 - (5%)

  Fly    16 LAHGIVGIIAFCVRLYMQGGKFRKQTDETGKVAIVTGGNTGLGKETVMELARRGATVYMACRNKE 80
            ||..:|.|:.|..|.|.:||:|.::....|.||:|||.|.|:|.|||.||..|.|.|||.||::|
 Worm    17 LASSVVFIVLFFTRRYFKGGQFNERVSAKGLVAVVTGSNCGIGFETVRELNLRKADVYMLCRSEE 81

  Fly    81 KVERARREIVKE-TGNSNVFSRECDLSSLDSIRKFAENFKKEQRVLHILINNAGV-FWEPHRLTK 143
            |...|:|.:|:: ...:.:...||||:..:|:|:.|:...:....:.|||||||: |...|..||
 Worm    82 KANEAKRMLVRQGCDATRLHFIECDLTDFESVRRAAKETLESTDTIDILINNAGIMFQSKHEQTK 146

  Fly   144 EGFEMHLGVNHIGHFLLTNLLLGVLERSAPSRVVVVASRAHERGQIKVDDINSSDFYDE---GV- 204
            :|.|.....||:|.||||.|.|..:::|:.:|::.|:||.|    :|.:.||.:...|:   |:
 Worm   147 DGHEKTWQSNHLGPFLLTELFLPAVKKSSYARIINVSSRIH----LKSEKINLATVDDKKSFGMM 207

  Fly   205 -AYCQSKLANILFTRELAKRLEGTG---VTVNALNPGIADTEIARNMIFFQTKFAQYVVETILRP 265
             :|.||||||::..|.|.|.|...|   ||||:|:||:.:||:|||.|.......|  :..:.|
 Worm   208 KSYRQSKLANVMHARALTKELRKDGAEHVTVNSLHPGVVNTELARNTILNTPGIKQ--ITAVFR- 269

  Fly   266 LLWAVMKTPKNGAQTTLYAALDPDLERVSGQYFSDCALAPVAPAALDDQMAQWLWAQS 323
              |.:|||.::||||:::.||...:..:||:||:||.|....|.|||||..|.|:..|
 Worm   270 --WFLMKTSRDGAQTSIFLALGKKIGGISGKYFADCKLTQENPLALDDQACQDLYNYS 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30495	NP_001260785.1	Rossmann-fold NAD(P)(+)-binding proteins	45..323	CDD:473865	118/287 (41%)
dhs-22	NP_506570.1	retinol-DH_like_SDR_c_like	46..322	CDD:212492	117/284 (41%)