DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30495 and Rdh11

DIOPT Version :9

Sequence 1:	NP_001260785.1	Gene:	CG30495 / 246651	FlyBaseID:	FBgn0050495	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_067532.2	Gene:	Rdh11 / 17252	MGIID:	102581	Length:	316	Species:	Mus musculus

Alignment Length:	314	Identity:	150/314 - (47%)
Similarity:	202/314 - (64%)	Gaps:	25/314 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GIVGIIAFCVRLYMQGGKFRKQTDE---------TGKVAIVTGGNTGLGKETVMELARRGATVYM 74
            |.:.:::....||:...|.||....         .||||||||.|||:||||..:||:|||.||:
Mouse     3 GFLLLLSLPFILYLVTPKIRKMLSSGVCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYL 67

  Fly    75 ACRNKEKVERARREIVKETGNSNVFSRECDLSSLDSIRKFAENFKKEQRVLHILINNAGVFWEPH 139
            |||:.:|.|.|.|||...||||.||.|:.||:...|||.||::|..|::.||:|||||||...|:
Mouse    68 ACRDVDKGELAAREIQAVTGNSQVFVRKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCPY 132

  Fly   140 RLTKEGFEMHLGVNHIGHFLLTNLLLGVLERSAPSRVVVVASRAHERGQIKVDDINSSDFYDEGV 204
            ..|.:|||||:||||:||||||:|||..|:.|||||:|.::|..|..|:|...::....||..|:
Mouse   133 SKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNLSSLGHHLGRIHFHNLQGEKFYSAGL 197

  Fly   205 AYCQSKLANILFTRELAKRLEGTGVTVNALNPGIADTEIARNMIFFQTKFAQYVVETILR---PL 266
            |||.|||||||||:||||||:|:|||..:::||...:|:.|             ..:|:|   .|
Mouse   198 AYCHSKLANILFTKELAKRLKGSGVTTYSVHPGTVHSELTR-------------YSSIMRWLWQL 249

  Fly   267 LWAVMKTPKNGAQTTLYAALDPDLERVSGQYFSDCALAPVAPAALDDQMAQWLW 320
            .:..:|||:.||||:||.||...||.:||.:||||.||.|:....::.:|:.||
Mouse   250 FFVFIKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIARRLW 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30495	NP_001260785.1	FabG	44..296	CDD:223959	133/254 (52%)
CG30495	NP_001260785.1	NADB_Rossmann	45..323	CDD:304358	144/279 (52%)
Rdh11	NP_067532.2	PRK06197	38..311	CDD:235737	144/279 (52%)
Rdh11	NP_067532.2	NADB_Rossmann	38..306	CDD:304358	144/279 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100724
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm8848
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.790