Protein Alignment CG30495 and RDH12

DIOPT Version :9

• Sequence 1: NP_001260785.1
• Gene: CG30495 / 246651
• FlyBaseID: FBgn0050495
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_689656.2
• Gene: RDH12 / 145226
• HGNCID: 19977
• Length: 316
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 155/318 - (48%)
• Similarity: 196/318 - (61%)
• Gaps: 31/318 - (9%)

  Fly     7 FLQSIAPVFLAHGIVGIIAFCVRLYMQGGKFRKQTDETGKVAIVTGGNTGLGKETVMELARRGAT 71
            ||..:||             .:|.:..||..|......|||.::||.|||:||||..|||.|||.
Human    14 FLYMVAP-------------SIRKFFAGGVCRTNVQLPGKVVVITGANTGIGKETARELASRGAR 65

  Fly    72 VYMACRNKEKVERARREIVKETGNSNVFSRECDLSSLDSIRKFAENFKKEQRVLHILINNAGVFW 136
            ||:|||:..|.|.|..||..:|.||.|..|:.|||...|||.|||.|..|::.||||||||||..
Human    66 VYIACRDVLKGESAASEIRVDTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMM 130

  Fly   137 EPHRLTKEGFEMHLGVNHIGHFLLTNLLLGVLERSAPSRVVVVASRAHERGQIKVDDINSSDFYD 201
            .|:..|.:|||.||||||:||||||.|||..|:.|||:|||.|:|.||..|:|...|:.|...|.
Human   131 CPYSKTADGFETHLGVNHLGHFLLTYLLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYS 195

  Fly   202 EGVAYCQSKLANILFTRELAKRLEGTGVTVNALNPGIADTEIARNMIFFQTKFAQYVVETILRPL 266
            .|.|||.|||||:||||||||||:|||||..|::||:..:|:.|:              :.|..|
Human   196 RGFAYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRH--------------SSLLCL 246

  Fly   267 LWAV----MKTPKNGAQTTLYAALDPDLERVSGQYFSDCALAPVAPAALDDQMAQWLW 320
            ||.:    :||.:.||||:|:.||...||.:||:|||||....|:|.|.:::.|:.||
Human   247 LWRLFSPFVKTAREGAQTSLHCALAEGLEPLSGKYFSDCKRTWVSPRARNNKTAERLW 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30495	NP_001260785.1	FabG	44..296	CDD:223959	135/255 (53%)
		NADB_Rossmann	45..323	CDD:304358	147/280 (53%)
RDH12	NP_689656.2	retinol-DH_like_SDR_c	39..307	CDD:212495	147/280 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		otm41333
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.790