Protein Alignment CG30495 and Rdh14

DIOPT Version :10

• Sequence 1: NP_001260785.1
• Gene: CG30495 / 246651
• FlyBaseID: FBgn0050495
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_076186.1
• Gene: Rdh14 / 105014
• MGIID: 1920402
• Length: 334
• Species: Mus musculus
• Alignment Length: 294
• Identity: 139/294 - (47%)
• Similarity: 191/294 - (64%)
• Gaps: 24/294 - (8%)

  Fly    45 GKVAIVTGGNTGLGKETVMELARRGATVYMACRNKEKVERA----RREIVKETG------NSNVF 99
            ||..::||.|:|||:.|..||.|.||.|.|.||::.:.|.|    |:|:.:..|      :..:.
Mouse    44 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDGTDGQLV 108

  Fly   100 SRECDLSSLDSIRKFAENFKKEQRVLHILINNAGVFWEPHRLTKEGFEMHLGVNHIGHFLLTNLL 164
            .:|.||:||.|:|.|.:...:|:..|.:||||||||..|:..|::||||..||||:|||||||||
Mouse   109 VKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFGVNHLGHFLLTNLL 173

  Fly   165 LGVLERSAPSRVVVVASRAHERGQIKVDDINSSDFYDEGVAYCQSKLANILFTRELAKRLEGTGV 229
            ||:|:.|||||:|||:|:.::.|:|..:|:||...|::...|.:|||||||||||||:|||||.|
Mouse   174 LGLLKSSAPSRIVVVSSKLYKYGEINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNV 238

  Fly   230 TVNALNPGIADTEIARNMIFFQTKFAQYVVETILRPLL----WAVMKTPKNGAQTTLYAALDPDL 290
            |||.|:|||..|.:.|::          .:..:.|||.    ||..|||..||||::|.|..||:
Mouse   239 TVNVLHPGIVRTNLGRHI----------HIPLLARPLFNLVSWAFFKTPLEGAQTSIYLACSPDV 293

  Fly   291 ERVSGQYFSDCALAPVAPAALDDQMAQWLWAQSE 324
            |.|||:||.||....:.|.|:|:.:|:.||..||
Mouse   294 EGVSGRYFGDCKEEELLPKAMDESVARKLWDISE 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30495	NP_001260785.1	Rossmann-fold NAD(P)(+)-binding proteins	45..323	CDD:473865	137/291 (47%)
Rdh14	NP_076186.1	Rossmann-fold NAD(P)(+)-binding proteins	44..326	CDD:473865	137/291 (47%)