DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30495 and dhrsx

DIOPT Version :9

Sequence 1:	NP_001260785.1	Gene:	CG30495 / 246651	FlyBaseID:	FBgn0050495	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	XP_002933664.3	Gene:	dhrsx / 100487450	XenbaseID:	XB-GENE-5952439	Length:	327	Species:	Xenopus tropicalis

Alignment Length:	293	Identity:	109/293 - (37%)
Similarity:	168/293 - (57%)	Gaps:	14/293 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 ETGKVAIVTGGNTGLGKETVMELARRGATVYMACRNKEKVERARREIVKETGNSNVFSRECDLSS 107
            :.|||||||||..|:|..|...|:..|..|.:|..|:.:...|...|.::|.|..|....|||:|
Frog    39 QNGKVAIVTGGAKGIGYSTAKHLSSLGMHVIIAGNNEAEGSEAVTRIQQDTHNEKVEFLYCDLAS 103

  Fly   108 LDSIRKFAENFKKEQRVLHILINNAGVFWEPHRLTKEGFEMHLGVNHIGHFLLTNLLLGVLERSA 172
            :.|||:|.:.||.:...||:|:|||||...|.|.|.:|||.|.|:|::||||||||||...:.|.
Frog   104 MKSIRQFVQIFKAKNLCLHVLVNNAGVMLVPERKTADGFEEHFGLNYLGHFLLTNLLLKTTKESG 168

  Fly   173 P----SRVVVVASRAHERGQIKVDDINSSDFYDEGVAYCQSKLANILFTRELAKRL--EGTGVTV 231
            .    :|::.|:|..|..|::..||:|||..|....||.|||||.::||..|.::|  :|..||.
Frog   169 TENLNARIITVSSATHYVGELNFDDLNSSCCYSPHGAYAQSKLALVMFTYYLQRQLSEDGCYVTA 233

  Fly   232 NALNPGIADTEIARNMIFFQTKFAQYVVETILRPLLWAVMKTPKNGAQTTLYAALDPDLERVSGQ 296
            |.::||:.:|::.|| :.:..:..:::...:.       .||.:.||.|::||::.|:||.:.|.
Frog   234 NVVDPGVVNTDLYRN-VCWPGRLVKWMAARLF-------FKTAEEGAATSIYASVAPELEGIGGC 290

  Fly   297 YFSDCALAPVAPAALDDQMAQWLWAQSEKWAKI 329
            |..:......|..:.::.:.:.||.:|.|...|
Frog   291 YLYNGQKTKSADISYNEDLQRKLWNESCKMVGI 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30495	NP_001260785.1	FabG	44..296	CDD:223959	101/257 (39%)
CG30495	NP_001260785.1	NADB_Rossmann	45..323	CDD:304358	106/283 (37%)
dhrsx	XP_002933664.3	retinol-DH_like_SDR_c_like	41..314	CDD:212492	104/280 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910