DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq9 and Coq9

DIOPT Version :9

Sequence 1:	NP_724594.1	Gene:	Coq9 / 246650	FlyBaseID:	FBgn0050493	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_080728.1	Gene:	Coq9 / 67914	MGIID:	1915164	Length:	313	Species:	Mus musculus

Alignment Length:	336	Identity:	108/336 - (32%)
Similarity:	164/336 - (48%)	Gaps:	56/336 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YKLIRLQKLLLPLNATSSRLAP-LQPRPLTFLIARSYGKDEKKANLEDFRAREEQRERERDAADQ 71
            ::|::|:  .||:    :|..| |.||.....:.              ||:.|||::       |
Mouse    16 WRLLQLR--CLPV----ARCRPALVPRAFHTAVG--------------FRSSEEQKQ-------Q 53

  Fly    72 AAEKASQKEAGGGGGLGAKGSESTGPE---------DDAKQAKVD-----AIRAKILDAALQHVP 122
            ....:||:.           ||:.|||         |.:.:.:.|     .::.:||.|||:.||
Mouse    54 PPHSSSQQH-----------SETQGPEFSRPPPRYTDQSGEEEEDYESEEQLQHRILTAALEFVP 107

  Fly   123 QQGWTRQAIILGAEESGYPSVVHGMFPEGGFALVSHFNGKCNA---QLVESLQQKTDGGKQEVED 184
            ..|||.:||..||:..|..|....||...|..|:.||..:|||   |::|..|:....|:.|...
Mouse   108 AHGWTAEAIAEGAQSLGLSSAAASMFGSDGSELILHFVTQCNARLNQVLEEEQKLVQLGQAEKRK 172

  Fly   185 PLDFLVQAVRQRLEMVTPYKTHWPQAMALLAQPQHAPTALAQVLTLVDDICYYSGDRSVDFGWYT 249
            ...||..||..||.|:.||..|||:|:::|..|.:.|.:|..:.::|||:.:|:||:|.||.|||
Mouse   173 TDQFLRDAVETRLRMLIPYIEHWPRALSILLLPHNIPPSLNLLTSMVDDMWHYAGDQSTDFNWYT 237

  Fly   250 RRVGLATIMKMTELYFLQDKSPGHAQTWEFLKSRMDEAVQLQMMLSQTEGMTHTFQRSFNSAFIT 314
            ||..||.|...|||..:||.||....||.||::|:::|:.:.....|.:.......:....|.:|
Mouse   238 RRAVLAGIYNTTELVMMQDSSPDFEDTWRFLENRINDAMNMGHTAKQVKSTGEALVQGLMGAAVT 302

  Fly   315 ARNILGLGYNR 325
            .:|:.||...|
Mouse   303 LKNLTGLNQRR 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq9	NP_724594.1	diverge_rpsU	110..297	CDD:274110	77/189 (41%)
Coq9	NP_724594.1	COQ9	217..287	CDD:285683	32/69 (46%)
Coq9	NP_080728.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..93		8/48 (17%)
		diverge_rpsU	97..276	CDD:274110	74/195 (38%)
		COQ9	205..275	CDD:285683	32/69 (46%)
		Lipid binding. /evidence=ECO:0000250\|UniProtKB:O75208	236..239		0/2 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837286
Domainoid	1	1.000	87	1.000	Domainoid score	I8006
eggNOG	1	0.900	-	-		E1_COG5590
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6477
Inparanoid	1	1.050	168	1.000	Inparanoid score	I4146
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55764
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006412
OrthoInspector	1	1.000	-	-		oto93604
orthoMCL	1	0.900	-	-		OOG6_104041
Panther	1	1.100	-	-	LDO	PTHR21427
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2073
SonicParanoid	1	1.000	-	-		X4676
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790