DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq9 and coq9

DIOPT Version :9

Sequence 1:	NP_724594.1	Gene:	Coq9 / 246650	FlyBaseID:	FBgn0050493	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001011181.1	Gene:	coq9 / 496601	XenbaseID:	XB-GENE-948680	Length:	317	Species:	Xenopus tropicalis

Alignment Length:	343	Identity:	110/343 - (32%)
Similarity:	165/343 - (48%)	Gaps:	47/343 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ANVRCLYKLIRLQKLLLPLNATSSRLAPLQPRPLTFLIARSYG------KDEKKANLEDFRAR-- 58
            |:|..:.|....::|||.:    :|..|:..:|...:..:.:|      :|:|:.......|.
Frog     3 ASVARVLKAAGGRQLLLMV----ARRRPVLRQPFLLMPRKFWGTSALRSEDQKQPPFSSTSAHAG 63

  Fly    59 -----EEQRERERDA---ADQAAEKASQKEAGGGGGLGAKGSESTGPEDDAKQAKVDAIRAKILD 115
                 |||.::::..   .|||                  |.||.|.|.:      :.::.:||.
Frog    64 TPEHAEEQYQQQQPPPRYTDQA------------------GEESEGYESE------EQLQQRILS 104

  Fly   116 AALQHVPQQGWTRQAIILGAEESGYPSVVHGMFPEGGFALVSHFNGKCNAQLVESLQQK---TDG 177
            ||||.||..||:..||..||:.....:...|||.:||..||.||..:||:||.|.|:::   ...
Frog   105 AALQFVPDFGWSADAIAEGAKSLDMSAAAAGMFEDGGSELVLHFVTQCNSQLTELLEEEQKLVQL 169

  Fly   178 GKQEVEDPLDFLVQAVRQRLEMVTPYKTHWPQAMALLAQPQHAPTALAQVLTLVDDICYYSGDRS 242
            |..|.:....||..||..||.|..||...||||:.:|..|::.|::|..:..:||||.:|:||:|
Frog   170 GTSEKKPTTQFLRDAVEARLRMHIPYIEQWPQALGMLLLPRNIPSSLKLLTAMVDDIWHYAGDQS 234

  Fly   243 VDFGWYTRRVGLATIMKMTELYFLQDKSPGHAQTWEFLKSRMDEAVQLQMMLSQTEGMTHTFQRS 307
            .|..|||||..|..|...|||..|||.||....||:||::|:.||:.:...:.|.........:.
Frog   235 TDVSWYTRRAVLTGIYNTTELVMLQDSSPDFEDTWKFLENRISEAMTMGTSVKQVASTGEAVIQG 299

  Fly   308 FNSAFITARNILGLGYNR 325
            ...|.:|.:|:.||...|
Frog   300 LMGAAVTLKNLTGLNQRR 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq9	NP_724594.1	diverge_rpsU	110..297	CDD:274110	79/189 (42%)
Coq9	NP_724594.1	COQ9	217..287	CDD:285683	32/69 (46%)
coq9	NP_001011181.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..97		14/75 (19%)
		TetR_C_23	99..289	CDD:393344	79/189 (42%)
		Lipid binding. /evidence=ECO:0000250\|UniProtKB:O75208	240..243		2/2 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	85	1.000	Domainoid score	I8076
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6477
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4067
OMA	1	1.010	-	-		QHG55764
OrthoDB	1	1.010	-	-		D1304924at2759
OrthoFinder	1	1.000	-	-		FOG0006412
OrthoInspector	1	1.000	-	-		oto103834
Panther	1	1.100	-	-	LDO	PTHR21427
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2073
SonicParanoid	1	1.000	-	-		X4676
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110