DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp12d1-p and CYP714A1

DIOPT Version :9

Sequence 1:	NP_001286304.1	Gene:	Cyp12d1-p / 246648	FlyBaseID:	FBgn0050489	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_568463.1	Gene:	CYP714A1 / 832560	AraportID:	AT5G24910	Length:	532	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	116/515 - (22%)
Similarity:	207/515 - (40%)	Gaps:	103/515 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAM---- 75
            ||..|....:|...::.:|.|....|.|                 .|:  |....:|||::
plant    49 GPPPSLFRGNVPEMQKIQSQIMSNSKHY-----------------SGD--NIIAHDYTSSLFPYL 94

  Fly    76 ---RKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRN------EGIWPRRDGLDSIVYFREHVRP 131
               ||:||.:|             |::|...:.::.|      |........|..:.|..:.::
plant    95 DHWRKQYGRVY-------------TYSTGVKQHLYMNHPELVKELNQANTLNLGKVSYVTKRLK- 145

  Fly   132 DVYGEVQGLVASQNEAWGKLRSAINPIFM--QPRGL-RMYYE---PLSNINNEFIERIKE-IRDP 189
            .:.|  :|::.|....|...|..|.|.|.  :.:|: .:..|   |:.:...|.::|..| :.|
plant   146 SILG--RGVITSNGPHWAHQRRIIAPEFFLDKVKGMVGLVVESAMPMLSKWEEMMKREGEMVCD- 207

  Fly   190 KTLEVPEDF----TDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALT----LFQTS--RDIFRL 244
              :.|.||.    .|.|||..|.|    :|.:...:..|.|....|:|    ||..:  .|:...
plant   208 --IIVDEDLRAASADVISRACFGS----SFSKGKEIFSKLRCLQKAITHNNILFSLNGFTDVVFG 266

  Fly   245 T-----FKLD-----IQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDALEKRRQAGEKIN 299
            |     .|:|     |:..:|:.:.    .:.:..:.|......:::.|           |.:.:
plant   267 TKKHGNGKIDELERHIESLIWETVK----ERERECVGDHKKDLMQLILE-----------GARSS 316

  Fly   300 SNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDS 364
            .:..||...:......|.....|.|||.:.:|..:|..|:.|:.:|..|.::|:|:  .:..|:.
plant   317 CDGNLEDKTQSYKSFVVDNCKSIYFAGHETSAVAVSWCLMLLALNPSWQTRIRDEV--FLHCKNG 379

  Fly   365 LLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYY 429
            :.:.:::.::..:..||:||||.||......|....|..|....||||..:......|.::...:
plant   380 IPDADSISNLKTVTMVIQETLRLYPPAAFVSREALEDTKLGNLVVPKGVCIWTLIPTLHRDPEIW 444

  Fly   430 -PRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNF 488
             ...:||.|||:   .|...|....|.:|:|||.|.|:|:||....:|::..|:.::..|
plant   445 GADANEFNPERF---SEGVSKACKHPQSFVPFGLGTRLCLGKNFGMMELKVLVSLIVSRF 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_001286304.1	p450	70..508	CDD:299894	106/460 (23%)
CYP714A1	NP_568463.1	p450	37..530	CDD:299894	116/515 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010