Protein Alignment Cyp12d1-p and cyp27b1

DIOPT Version :9

• Sequence 1: NP_001286304.1
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001298720.1
• Gene: cyp27b1 / 793309
• ZFINID: ZDB-GENE-111005-2
• Length: 505
• Species: Danio rerio
• Alignment Length: 503
• Identity: 137/503 - (27%)
• Similarity: 245/503 - (48%)
• Gaps: 53/503 - (10%)

  Fly    36 TEEHKTYDEIPRPNKFKFMR-AFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFN 99
            |.:.||.:::|.|:..:|:| .||..|   .:.:.:.....|::||.::  ...||....|....
Zfish    35 TPQVKTLEQMPGPSPARFIRDLFMKRG---FSRLHQLQLEGRQKYGPMW--KASFGPILTVHVAE 94

  Fly   100 TKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRG 164
            .:.|:.|.|.||..|.|..|.|...:|.     :.||..||:.::.|.|..:||.::...::|:.
Zfish    95 PELIQQVLRQEGQHPVRSELSSWKDYRA-----LRGEGYGLLTAEGEEWQCVRSLLSKHMLRPQA 154

  Fly   165 LRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNS 229
            :..|...|:.:.::.::::|......:..:..|.:.|..|...|.:..|.|:.::|.:
Zfish   155 VEAYDGALNAVVSDLLQKLKLRSQESSSRIVSDISAEFYRFGLEGISSVLFESRIGCL------- 212

  Fly   230 DALTLFQTSRDI------FRLTFKLDIQPSMW--KIISTP--TYRKMKRTLNDSL--NVAQKMLK 282
            ||:...:|.|.|      |.:|. |.:....|  :::..|  |:.:....:.:..  ::.|::.:
Zfish   213 DAVVPVETERFIQSINTMFVMTL-LTMAMPQWLHRLLPKPWDTFCRCWDVMFEFAKGHIDQRLQE 276

  Fly   283 ENQDALEKRRQAGEKINSNSMLERLMEID-PKVAVIMSL-DILFAGVDATATLLSAVLLCLSKHP 345
            |.|     :.:.||::....:...|.:.. |..:|..:: ::|.||||..::.||..|..||:||
Zfish   277 EKQ-----KLECGEQLEGRYLTYFLSQAGLPLTSVYSNVTELLLAGVDTISSTLSWSLYELSRHP 336

  Fly   346 DKQAKLREELLSIMPTKD-SLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRV 409
            |.|..||:|:||:|  || |:....::..||.|:||:||.||.||......|....|:.:.||.:
Zfish   337 DVQTALRDEVLSVM--KDRSVPQASDVAAMPLLKAVVKEILRLYPVIPANARVINKDIEVGGYVI 399

  Fly   410 PKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVS-PFTFLPFGFGPRMCIGKRVV 473
            ||.|.:.|......::...:..||.|.|:||      |.:...| |:..:|||.|.|.|||:|:.
Zfish   400 PKNTLITLCHYATSRDPQQFRDPDSFRPQRW------GDRSDRSHPYATVPFGVGKRSCIGRRIA 458

  Fly   474 DLEMETTVAKLIRNFHVEFNR--DASRPF-KTMFVMEPAITFPFKFTD 518
            :||:...:::::.:|.:|..|  |...|. :|:.|.|..|  ..:||:
Zfish   459 ELEVYLALSRILMHFTMEPVRENDTVHPMTRTLLVPERQI--DLRFTE 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_001286304.1	p450	70..508	CDD:299894	123/456 (27%)
cyp27b1	NP_001298720.1	p450	45..493	CDD:278495	129/478 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3547
OMA	1	1.010	-	-		QHG48087
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.980