Protein Alignment Cyp12d1-p and cyp46a1.1

DIOPT Version :9

• Sequence 1: NP_001286304.1
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001018358.1
• Gene: cyp46a1.1 / 553543
• ZFINID: ZDB-GENE-050522-464
• Length: 501
• Species: Danio rerio
• Alignment Length: 524
• Identity: 119/524 - (22%)
• Similarity: 221/524 - (42%)
• Gaps: 120/524 - (22%)

  Fly    39 HKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSA-----------MRKRYGDIYVMPGMFGRK 92
            |:.||.||.|.:..|:..       .::|:|:...:           ..::||.:|    .....
Zfish    32 HQKYDHIPGPPRDSFLLG-------HSSSLTKAVYSDNNLIHDLFLHWAEKYGPVY----RINTL 85

  Fly    93 DWVTTF-----NTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEV----------QGLV- 141
            .:||..     .||.|.|               |..|.::   |.||.::          .||:
Zfish    86 HYVTIMVYCPEATKTIMM---------------SPKYIKD---PFVYKQLFNLFGKRFLGNGLIT 132

  Fly   142 ASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLV 206
            |..::.|.:.|..::|.|.... ||........::...:::::|:.:.||   |....|.::.:.
Zfish   133 AVDHDMWYRQRRIMDPAFSSTY-LRSLISTFDEMSERLMDKLEEMANNKT---PAVMHDLVNCVT 193

  Fly   207 FESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQ-------PSMWKII-----S 259
            .:.:..|||...:.|:  |:.:|.    ||.:.::......||::       |..||:|     :
Zfish   194 LDVICKVAFGVDLNLL--NQKDSP----FQNAVELCLKGMILDVRDPFFRLFPKNWKLIQQVREA 252

  Fly   260 TPTYRK--------MKRTLNDSLNVAQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAV 316
            |...||        .|..:.:..:|.:.:|.:...:.|:     |.:|:...||::::
Zfish   253 TELLRKTGEKWIQNRKTAVKNGEDVPKDILTQILKSAEE-----ENVNNTQDLEQMLD------- 305

  Fly   317 IMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVI 381
             ..:....||.:.||..||..::.|.::|:...:.:.|:..::.||..:.||: :..:.||..|:
Zfish   306 -NFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTKREISNED-LGKLTYLSQVL 368

  Fly   382 KETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPET 446
            |||||.||...||.|....|::::|.:||:|.:|:..|.|..:...::..|.:|.|||:  |...
Zfish   369 KETLRLYPTAPGTNRWLHEDIVINGIKVPRGCSVMFSSYVSQRLEKFFKDPLKFDPERF--DVNA 431

  Fly   447 GKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFVMEPAIT 511
            .|..    :.:.||..|||.|:|:....:|.:..:|||::.|.              |.:.|..:
Zfish   432 PKPY----YCYYPFSLGPRTCLGQVFAQMEAKLVLAKLLQRFE--------------FSLVPGQS 478

  Fly   512 FPFK 515
            |..|
Zfish   479 FDIK 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_001286304.1	p450	70..508	CDD:299894	107/484 (22%)
cyp46a1.1	NP_001018358.1	p450	39..495	CDD:278495	115/517 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010