Protein Alignment Cyp12d1-p and Cyp12a4

DIOPT Version :9

• Sequence 1: NP_001286304.1
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 217/507 - (42%)
• Similarity: 331/507 - (65%)
• Gaps: 12/507 - (2%)

  Fly    24 SVLAHEQAKSSITEEHKTYDEIPRPNKFKF-MRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPG 87
            :|...|..:.|...:.|.:::|||.|.:.. |:..||||:::|..:.|...|||:.||||:.|||
  Fly    29 NVATAEAREDSEWLQAKPFEQIPRLNMWALSMKMSMPGGKYKNMELMEMFEAMRQDYGDIFFMPG 93

  Fly    88 MFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLR 152
            :.|...:::|.|.:|.|:||||||:||.|.|..:::|.||..|.|.|..|.|::.:|.:.||..|
  Fly    94 IMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFR 158

  Fly   153 SAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDR 217
            :.:||:.|||:.:|:||:.:|.:|.||::||.|:|||.|||.|:||.|.|:|...||:.:||.|:
  Fly   159 TVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVALDK 223

  Fly   218 QMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLK 282
            |:||::.:...|:||.||....:.|.::..|:::||.|:.|.||..:::.|.|:....|....:.
  Fly   224 QLGLLKNSNKESEALKLFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAYVD 288

  Fly   283 ENQDALEKRRQAG--EKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHP 345
            |..:.|:|..:.|  ...|..|:||:|:::|.|||.:|::|:|.||||.|::..:|:||||:|:|
  Fly   289 EAIERLDKEAKEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNP 353

  Fly   346 DKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVP 410
            :|||:||||::.::|.|:|...|.:||::|||||.|||:.|.:|..:|..|....|.:|||||||
  Fly   354 EKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVP 418

  Fly   411 KGTTV-LLGSNVLMKEATYYPRPDEFLPERWLRDPETGKK-------MQVSPFTFLPFGFGPRMC 467
            .||.| ::..|.|.:: .|:|:..|||||||||.|:..:.       ...:||.|||||||||||
  Fly   419 AGTYVNIVPLNALTRD-EYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMC 482

  Fly   468 IGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFVMEPAITFPFKFTDI 519
            :|||:|::|:|...|:|||||:||||......|::..:..|.|...|||.|:
  Fly   483 VGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSALINLPNIPLKFKFIDL 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_001286304.1	p450	70..508	CDD:299894	197/447 (44%)
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	200/459 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445013
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3547
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	10	9.900