Protein Alignment Cyp12d1-p and Cyp12a5

DIOPT Version :10

• Sequence 1: NP_610635.4
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 492
• Identity: 222/492 - (45%)
• Similarity: 326/492 - (66%)
• Gaps: 14/492 - (2%)

  Fly    40 KTYDEIPRPNKFK-FMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDI 103
            |.::|||:.|... |.::.:|||:::|..:.|...|:|:.||:|..:|||.||...|.|.|.||.
  Fly    45 KPFEEIPKANILSLFAKSALPGGKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDF 109

  Fly   104 EMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMY 168
            |:||||||:||.|.|.|.:.|.|...|.|.:..|||::.||.::||..||.:||:.|||:.:|:|
  Fly   110 EVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLY 174

  Fly   169 YEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALT 233
            ::.:|.:|.||:|.||||||..|.|||.:|.:.|:|...||:.:||.|:|:||:|::..||:|..
  Fly   175 FKKMSQVNQEFVELIKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEATK 239

  Fly   234 LFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDALEKRRQAG--E 296
            ||:...:.|..:..|:::||:|:...||..:||.||::....|..|.:.|..:.|||..:.|  .
  Fly   240 LFKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVR 304

  Fly   297 KINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPT 361
            ..:..|:||:|:::|.|||.:|::|:|.||||.|::..:|:||||:|:|:|||:||||::.::|.
  Fly   305 PEHEQSVLEKLLKVDKKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPN 369

  Fly   362 KDSLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTV-LLGSNVLMKE 425
            |||...|.:||::|||||.|||:.|.||..:|..|....|.::||||||.||.| ::..|.|..|
  Fly   370 KDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSE 434

  Fly   426 ATYYPRPDEFLPERWLRD--------PETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVA 482
             .|:|:|.|||||||||:        |....|.: :||.|||||||||||:|||:|::|:|...|
  Fly   435 -EYFPKPTEFLPERWLRNASDSAGKCPANDLKTK-NPFVFLPFGFGPRMCVGKRIVEMELELGTA 497

  Fly   483 KLIRNFHVEFNRDASRPFKTMFVMEPAITFPFKFTDI 519
            :|||||:||||......|::..:..|.|...|||||:
  Fly   498 RLIRNFNVEFNHSTKNAFRSALINLPNIPLKFKFTDV 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_610635.4	CYP24A1-like	76..508	CDD:410677	203/442 (46%)
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	205/447 (46%)