Protein Alignment Cyp12d1-p and Cyp313a1

DIOPT Version :10

• Sequence 1: NP_610635.4
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Alignment Length: 495
• Identity: 115/495 - (23%)
• Similarity: 197/495 - (39%)
• Gaps: 112/495 - (22%)

  Fly    44 EIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIY---VMPGMFGRKDWVTTFNTKDIEM 105
            :||.|.....:     |...:|....:...:.|.:|.:.|   ::..| |...::.|.:.|.:|.
  Fly    31 KIPGPIGLPIL-----GSSLENIITYKRKLSFRTKYLNKYGSTILTWM-GPVPFIVTRDPKVVED 89

  Fly   106 VFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQ------------GLVASQNEAWGKLRSAINPI 158
            :|.:                     ||.:.:.|            ||:..|:..|...|...||.
  Fly    90 IFSS---------------------PDCHNKSQHIVNAITSCMGNGLLGKQDPHWLDRRKHFNPS 133

  Fly   159 FMQPRGLRMYY------EPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDR 217
            |.|...|..::      :.|.|:.:.:::: .||          |...|:.|..|:    :|...
  Fly   134 FKQDLLLSFFHIFDAETKVLMNLLDTYVDK-GEI----------DVVPEMLRWSFK----IAAQT 183

  Fly   218 QMGLIRKNRD---NSDALTLFQT--SRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVA 277
            .||...|:.:   |...:..|::  |.....:...|.....:.||..   |.|::.   |:.:..
  Fly   184 TMGSEVKHDEHFKNGSLVESFESLISHSTLNILMPLVQNRMISKICG---YDKLRA---DNFSRI 242

  Fly   278 QKMLKENQDALEKRRQAGEKIN----------SNSMLERLMEIDPKVAVIMSLDI-------LFA 325
            ||||.         ....:|:|          ||.::.|.||:..| ..|..:|:       :.|
  Fly   243 QKMLD---------NVVNKKVNPLPKTDSDPESNIVINRAMELYRK-GDITYMDVKSECCIMIAA 297

  Fly   326 GVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSL-LNEENMKDMPYLRAVIKETLRYYP 389
            |.|.:|..:...|..|:.||:.|..:.|||..:.|..... :...:|:.:.||..|||||||..|
  Fly   298 GYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIKETLRLIP 362

  Fly   390 NGLGTMRTCQNDVILS-GYRVPKGTTVLLGSNVL---MKEATYYPRPDEFLPERWLRDPETGKKM 450
            ....|.|..:|||.|| |..:|||  |::|.::.   .....:.|..|.|.|:.:|.:    ...
  Fly   363 AIPITARETKNDVRLSNGVLIPKG--VVIGIDMFHTHRNPEVWGPDADNFNPDNFLAE----NME 421

  Fly   451 QVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHV 490
            |..|:.::||..|.|.|||.:...:..:..:.:::||:.:
  Fly   422 QKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKI 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_610635.4	CYP24A1-like	76..508	CDD:410677	110/463 (24%)
Cyp313a1	NP_650368.1	CYP313-like	66..487	CDD:410680	107/455 (24%)