Protein Alignment Cyp12d1-p and cyp46a1.4

DIOPT Version :9

• Sequence 1: NP_001286304.1
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_005160404.1
• Gene: cyp46a1.4 / 393451
• ZFINID: ZDB-GENE-040426-1224
• Length: 501
• Species: Danio rerio
• Alignment Length: 526
• Identity: 117/526 - (22%)
• Similarity: 211/526 - (40%)
• Gaps: 120/526 - (22%)

  Fly    39 HKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDI 103
            |:.||.||.|.:..|:....|             |..:..|.|..::..:|  ..|...:..
Zfish    32 HQKYDHIPGPPRDNFLFGHSP-------------SLTKSMYADDSLIHDLF--LQWAEKYGP--- 78

  Fly   104 EMVFRNEGIWPRRDGLDSIVYFREHVR-----------------PDVYGEV----------QGLV 141
              |:|          ::|:.|....|.                 |.||..:          .||:
Zfish    79 --VYR----------INSLHYIAIVVHCPEATKTILMSPKYTKDPFVYRRLFNLFGKRFLGYGLI 131

  Fly   142 -ASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRL 205
             |..::.|.:.|..::|.|.... ||........::...:::::|:.:.||   |....|.::.:
Zfish   132 TAVDHDIWYRQRRIMDPAFSSSY-LRSLISTFDEMSERLMDKLEEMANNKT---PAVMHDLVNCV 192

  Fly   206 VFESLGLVAFDRQMG-LIRKNRDNSDALTLFQTS-----RDIFRLTFKLDIQPSMWKII-----S 259
            ..:.:..|||...:. |.:|:....:|:.|....     ||.|...|     |..||:|     :
Zfish   193 TLDVICKVAFGVDLNFLAQKDSPFQNAVELCLNGMTVDLRDPFFRLF-----PKNWKLIHQIRDA 252

  Fly   260 TPTYRK--------MKRTLNDSLNVAQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAV 316
            ....||        .|..:.:..:|.:.:|.:...:.|:     |.:|:...||::::
Zfish   253 AELLRKTGEKWIQNRKTAVKNGEDVPKDILTQILKSAEE-----ENVNNTDDLEQMLD------- 305

  Fly   317 IMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVI 381
             ..:....||.:.||..||..::.|.::|:...:.:.|:..::.||..:.||: :....||..|:
Zfish   306 -NFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTKREISNED-LGKFTYLSQVL 368

  Fly   382 KETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPET 446
            |||||.||...||.|....|::::|.::|.|.:|:..|.|..:...::..|.:|.|||:  |...
Zfish   369 KETLRLYPTAPGTNRWLHEDMVINGIKIPGGCSVMFSSYVSQRLEKFFKDPLKFDPERF--DVNA 431

  Fly   447 GKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFVMEPAIT 511
            .|..    :.:.||..|||.|:|:....:|.:..:|||::.|.              |.:.|..:
Zfish   432 PKPY----YCYFPFALGPRTCLGQVFSQMEAKVVLAKLLQRFE--------------FSLVPGQS 478

  Fly   512 FPFKFT 517
            |..|.|
Zfish   479 FDIKDT 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_001286304.1	p450	70..508	CDD:299894	105/484 (22%)
cyp46a1.4	XP_005160404.1	p450	39..495	CDD:278495	113/519 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920