Protein Alignment Cyp12d1-p and Cyp301a1

DIOPT Version :10

• Sequence 1: NP_610635.4
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 158/534 - (29%)
• Similarity: 271/534 - (50%)
• Gaps: 52/534 - (9%)

  Fly    19 SSRSASVLAH--EQAKSSITEEHKT--------YDEIPRP-------NKFKFMRAFMPGGEFQNA 66
            ||...:...|  :..::|....|.|        |::||.|       |.::.|...   |::..:
  Fly    39 SSTGVATCPHLADSEEASAPRIHSTSEWQNALPYNQIPGPKPIPILGNTWRLMPII---GQYTIS 100

  Fly    67 SITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRP 131
            .:.:.:|.:..|||.|....|:.||.|.:..::..:||..:|:||..|.|..:.|:|.::..||.
  Fly   101 DVAKISSLLHDRYGRIVRFGGLIGRPDLLFIYDADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRK 165

  Fly   132 DVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPE 196
            |.:|::.|:|....|.|.:.||.:....:|...:|.|.:||..|..:|:.|.:.:.| :..|:||
  Fly   166 DFFGDLGGVVGVHGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENLLD-ENQELPE 229

  Fly   197 DFTDEISRLVFESLGLVAFDRQMGLIRKN-RDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIIST 260
            ||.:||.:...|.:|.||.|.::|.:..| :.:|:...:...::...|....|:::...|:...|
  Fly   230 DFDNEIHKWSLECIGRVALDTRLGCLESNLKPDSEPQQIIDAAKYALRNVATLELKAPYWRYFPT 294

  Fly   261 PTYRKMKRTLNDSLNVAQKMLKENQDALEKRR------QAGEKINSNSMLER--LMEIDPKVAVI 317
            |.:.:..:.:|..:.|..|.:   |.|.|:.:      :|||.    |::|:  |.:.|.|:|.|
  Fly   295 PLWTRYVKNMNFFVGVCMKYI---QSATERLKTQDPSLRAGEP----SLVEKVILSQKDEKIATI 352

  Fly   318 MSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIK 382
            |:||::..|:|..:..:.::|..|:..|..|.|:.|||..::|..::.|....:..|.:|:..||
  Fly   353 MALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIK 417

  Fly   383 ETLRYYPNGLGTMRTCQNDVILSGYRVPKGT-----TVLLGSNVLMKEATYYPRPDEFLPERWLR 442
            |..|.|...:|..||...|.::.||:||||.     |::.|:   |:|  |......|.|||||:
  Fly   418 EVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGN---MEE--YVTDAATFRPERWLK 477

  Fly   443 DPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRP--FKTMFV 505
            ....|...::.||..||:|:|.|||:|:|..||||:..:|||:||:.:|:|.   :|  :...|:
  Fly   478 PQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLEYNH---KPLDYAVTFM 539

  Fly   506 MEPAITFPFKFTDI 519
            ..|.....||.|.:
  Fly   540 YAPDGPLRFKMTRV 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_610635.4	CYP24A1-like	76..508	CDD:410677	140/447 (31%)
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	141/452 (31%)