Protein Alignment Cyp12d1-p and Cyp11b3

DIOPT Version :9

• Sequence 1: NP_001286304.1
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_861545.1
• Gene: Cyp11b3 / 353498
• RGDID: 727886
• Length: 498
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 125/514 - (24%)
• Similarity: 221/514 - (42%)
• Gaps: 90/514 - (17%)

  Fly    33 SSITEEHKT---YDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDW 94
            |:.|:..||   ::.||:.::.|:::......|....::........:..|.|:....  |....
  Rat    25 STATQAPKTLKPFEAIPQYSRNKWLKMIQILREQSQENLHLEMHQAFQELGPIFRHSA--GGAQI 87

  Fly    95 VTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIF 159
            |:....:|.|.:.:.|.|.|||..|:|.|..||     :.|..:|:.......|...|..:||..
  Rat    88 VSVMLPEDAEKLHQVESILPRRMTLESWVAHRE-----LRGLRRGVFLLNGADWRFNRLQLNPNM 147

  Fly   160 MQPRGLRMYYEPLSNINNEFIERIKE-----IRDPKTLEVPE---DFTDEISRLVF--ESLGLVA 214
            :.|:.::.:...:..:..:|:|.:|:     :....::::..   ::|.|.|..|.  |.|||..
  Rat   148 LSPKAVQSFVPFVDVVARDFVENLKKRMLENVHGSMSMDIQSNVFNYTMEASHFVISGERLGLTG 212

  Fly   215 FDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQP----------------SMWKIIS---- 259
            .|.          |.::|........:|:.|.:|...|                ..|.|||
  Rat   213 HDL----------NPESLKFIHALHSMFKSTTQLMFLPKNLTRWTSTQVWKGHFESWDIISEYVT 267

  Fly   260 ---TPTYRKMKRTLNDSLNVAQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLD 321
               ...||::......|.:|..:|:.::..::       :.|::|||                 :
  Rat   268 KCIKNVYRELAEGRQQSWSVISEMVAQSTLSM-------DAIHANSM-----------------E 308

  Fly   322 ILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLL--NEENMKDMPYLRAVIKET 384
            ::...||.||..|...|..|:::||.|..||:|.|:   .:.|:.  .::.|.|:|.|||.:|||
  Rat   309 LIAGSVDTTAISLVMTLFELARNPDVQQALRQESLA---AEASIAANPQKAMSDLPLLRAALKET 370

  Fly   385 LRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKK 449
            ||.||.|....|...:|::|..|.||.||.|::....:.:....:|||:.::|:|||....:
  Rat   371 LRLYPIGSSLERIVDSDLVLQNYHVPAGTLVIIYLYSMGRNPAVFPRPERYMPQRWLERKRS--- 432

  Fly   450 MQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFVMEP 508
                 |..|.||||.|.|:|:|:.::|:...:..:::.|.||..|.........||:.|
  Rat   433 -----FQHLAFGFGVRQCLGRRLAEVEVLLLLHHMLKIFQVETLRQEDVQMAYRFVLMP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_001286304.1	p450	70..508	CDD:299894	116/472 (25%)
Cyp11b3	NP_861545.1	p450	41..494	CDD:278495	120/498 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820