Protein Alignment Cyp12d1-p and Cyp11a1

DIOPT Version :9

• Sequence 1: NP_001286304.1
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_058982.1
• Gene: Cyp11a1 / 29680
• RGDID: 69325
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 550
• Identity: 134/550 - (24%)
• Similarity: 242/550 - (44%)
• Gaps: 91/550 - (16%)

  Fly     8 RSVAI-----YVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRP------NKFKFMRAFMPGG 61
            |||.:     ::.||  .:...:.....|..|.|...::::|||.|      |.:.|:|
  Rat     9 RSVLVKSCQPFLSPV--WQGPGLATGNGAGISSTNSPRSFNEIPSPGDNGWINLYHFLR------ 65

  Fly    62 EFQNASITEYTSAMR--KRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDS-IV 123
              :|.:...:...|:  ::||.||  ....|..:.|...:.||...:|..||..|.|..:.. :.
  Rat    66 --ENGTHRIHYHHMQNFQKYGPIY--REKLGNMESVYILDPKDAATLFSCEGPNPERYLVPPWVA 126

  Fly   124 YFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERI-KEIR 187
            |.:.:.||      .|::...::||.|.|..:|...|.|..::.:...|..:..:||:.: :.|:
  Rat   127 YHQYYQRP------IGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVLHRRIK 185

  Fly   188 DPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNS-----DAL-TLFQTSRDIFRLTF 246
            ...:.:...|.:|::.|..|||:..|.|..::|::.:..|..     ||: .:|.||..:
  Rat   186 QQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFHTSVPM----- 245

  Fly   247 KLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDALEKRRQ------------AGEKIN 299
             |::.|.::::..|.|::......:...:.|.:..:.....|.::|.            .|.|:.
  Rat   246 -LNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKRDFSKYPGVLYSLLGGNKLP 309

  Fly   300 SNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDS 364
            ..::...:.|            :|..|||.|:..|...|..::.:...|..||.|:|:
  Rat   310 FKNIQANITE------------MLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLA------- 355

  Fly   365 LLNEENMKDM-------PYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVL 422
             ...:...||       |.|:|.||||||.:|..:...|...||::|..|::|..|.|.:.|..:
  Rat   356 -ARRQAQGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAM 419

  Fly   423 MKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRN 487
            .:|::::|.|::|.|.|||.     |....:.|.:|.||:|.|.|:|:|:.:|||...:..::.|
  Rat   420 GRESSFFPNPNKFDPTRWLE-----KSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLEN 479

  Fly   488 FHVEFN--RDASRPFKTMFVMEPAITFPFK 515
            |.:|..  ||....|..:.:.|..|.|.|:
  Rat   480 FRIEVQSIRDVGTKFNLILMPEKPIFFNFQ 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_001286304.1	p450	70..508	CDD:299894	114/468 (24%)
Cyp11a1	NP_058982.1	cytochrome_P450	80..505	CDD:425388	114/463 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820