Protein Alignment Cyp12d1-p and cyp24a1

DIOPT Version :9

• Sequence 1: NP_001286304.1
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_012808417.2
• Gene: cyp24a1 / 100497429
• XenbaseID: XB-GENE-479201
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 552
• Identity: 148/552 - (26%)
• Similarity: 254/552 - (46%)
• Gaps: 103/552 - (18%)

  Fly    13 YVGPVRSSRSASV---LAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPG-------GEF---- 63
            ::|.:..|||.||   :....|...:.||     |:|.|:......|.:||       |..
 Frog     9 FLGMLLKSRSISVQHSIPTATAVCDLKEE-----ELPAPSSCPHSLAALPGPTKLPILGSLLDIL 68

  Fly    64 -------QNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDS 121
                   |:.::..|    .|::|.|:.|  ..|..|.|.......:|.::|.|..:|:|..:..
 Frog    69 RKGGLKRQHEALASY----HKQFGKIFRM--KLGSFDSVHIGAPCLLEALYREESNYPKRLEIKP 127

  Fly   122 IVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEI 186
            ...:|:: |.:.|    ||:..:.:.|.::|||.....|:|..:......::.:..:|::||..:
 Frog   128 WKAYRDY-RDEAY----GLLILEGKDWQRVRSAFQQKLMKPTEVGKLDTKINEVLVDFMKRIDSV 187

  Fly   187 RDPK-TLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDI 250
            .|.. |:   ||...|:::...||:.||.::::.|.::.|.  .:....|.|:..:...||.|
 Frog   188 CDEDGTI---EDLYCELNKWSLESICLVLYEKRFGFLQPNL--GEEAQNFITAIKMMMSTFGL-- 245

  Fly   251 QPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDALEK----------RRQAGEKINSNSMLE 305
                  ::.||.      .|:.|||.  |:.|::..|.:.          ||..  |::|....:
 Frog   246 ------MMVTPV------ELHKSLNT--KIWKDHTHAWDSIFKTAKCHIDRRLT--KLSSKGSED 294

  Fly   306 RLMEI--DPKV------AVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIM--- 359
            .|..|  |.|:      |.|  .::|...|:.||..|...:..:|::|..|.||.||:.|::
 Frog   295 FLCTIYNDSKLSKKEMYATI--TEMLIGAVETTANSLLWAIFNISRNPHIQKKLLEEIESVLLPD 357

  Fly   360 --PTKDSLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVL 422
              ||.|.:.|      ||||:|.:||::|..|:...|.||...:.:|..|.:||||.:.:.|:||
 Frog   358 QVPTADDIRN------MPYLKACLKESMRITPSIPFTTRTLDKETVLGDYVLPKGTVLTINSHVL 416

  Fly   423 MKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRN 487
            ......:...::|.|||||:...|     ::||..:|||.|.|||||:|:.:|:::.|:..|||.
 Frog   417 GSNQECFDNWNQFRPERWLQQKNT-----INPFAHVPFGIGKRMCIGRRLAELQLQLTLCWLIRK 476

  Fly   488 FH-VEFNRDASRPFKTMFV--MEPAITFPFKF 516
            :. |..:.|   |.:|:.:  :.|:...|..|
 Frog   477 YEIVATDND---PVETLHLGTLMPSRELPVAF 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-p	NP_001286304.1	p450	70..508	CDD:299894	128/464 (28%)
cyp24a1	XP_012808417.2	CYP24A1	84..502	CDD:410738	128/463 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3591
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm9361
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970