DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment antr and CRISPLD2

DIOPT Version :9

Sequence 1:	NP_001246284.1	Gene:	antr / 246647	FlyBaseID:	FBgn0050488	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_113664.1	Gene:	CRISPLD2 / 83716	HGNCID:	25248	Length:	497	Species:	Homo sapiens

Alignment Length:	231	Identity:	48/231 - (20%)
Similarity:	79/231 - (34%)	Gaps:	48/231 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 KTGILSRINMLRNYVASGVGNYSVAARMPTMGWDFELQRLADRQVRQCD-ETG----------KF 116
            |..||...|.||..|.....|      |..|.||.||::.|.....||. |.|          ..
Human    56 KEEILMLHNKLRGQVQPQASN------MEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNL 114

  Fly   117 CANTDKYHYVATTEIRSKMGRTKSLKSAILDKLLPELFLDVMGCMMNSQKLVPVR-EGTCVGHYM 180
            .|:..:|        ||.....:|....:.|...|        .........|.| .|....||.
Human   115 GAHWGRY--------RSPGFHVQSWYDEVKDYTYP--------YPSECNPWCPERCSGPMCTHYT 163

  Fly   181 PLIQDHGSRMGCGLRVKGR-----DEKESNIILLCHFS-RASVNNLVPYEEGQIPAGKC--ATGP 237
            .::....:::||.:....:     :..|:.:..:|::| :.:.....||:.|: |..:|  :.|.
Human   164 QIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGR-PCSECPPSYGG 227

  Fly   238 SQMYQFLCSEDEY-----VDANSMVVESNMPSSDQI 268
            |........|:.|     .|..:.|..:.:|..:.:
Human   228 SCRNNLCYREETYTPKPETDEMNEVETAPIPEENHV 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
antr	NP_001246284.1	SCP_euk	63..213	CDD:240180	35/166 (21%)
CRISPLD2	NP_113664.1	SCP_euk	56..201	CDD:240180	35/166 (21%)
		LCCL	286..370	CDD:128866
		LCCL	387..479	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750