DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30486 and Crispld1

DIOPT Version :9

Sequence 1:	NP_725234.2	Gene:	CG30486 / 246645	FlyBaseID:	FBgn0050486	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001343480.1	Gene:	Crispld1 / 83691	MGIID:	1934666	Length:	500	Species:	Mus musculus

Alignment Length:	228	Identity:	50/228 - (21%)
Similarity:	78/228 - (34%)	Gaps:	70/228 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 DFRNTVAKGQYPHLRPASRMATLRWHEELAGLAKFALRRCDYIDDYCSNTDEFSYVSYIYGSTKW 134
            |..|.:....||   .||.|..:.|..||...|:.....|                       .|
Mouse    67 DLHNKLRSQVYP---TASNMEYMTWDVELERSAESWAEMC-----------------------LW 105

  Fly   135 LQLEKDPISVL-----------------DFVLQFWMDDVKGCTMAHINAEKPAKDGQCRG----Y 178
               |..|.|:|                 .|.:|.|.|:|:..:..:.|...|....:|.|    :
Mouse   106 ---EHGPASLLPSIGQNLGAHWGRYRPPTFHVQAWYDEVRDFSYPYENECDPYCPFRCSGPVCTH 167

  Fly   179 FTQLVQDLAAHVGCAMMLRK-----GQ--TSGLYQYGVLCHFS-RGKIANELVYRASAHPGSRC- 234
            :||:|...::.:|||:.|..     ||  ...:|   ::|::| :|.......|: ...|.|.|
Mouse   168 YTQVVWATSSRIGCAVNLCHNMNIWGQIWPKAVY---LVCNYSPKGNWWGHAPYK-HGRPCSACP 228

  Fly   235 --YAGTHSIYEGLCSPE---EHVNPNALQLGEL 262
              :.|  ...|.||..|   .:..|...:..|:
Mouse   229 PSFGG--GCRENLCYKEGSDRYYTPREEETNEI 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30486	NP_725234.2	SCP_euk	61..214	CDD:240180	37/171 (22%)
Crispld1	NP_001343480.1	CAP_CRISPLD1	62..207	CDD:349407	37/171 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	258..281		1/2 (50%)
		LCCL	291..375	CDD:128866
		LCCL	394..492	CDD:367672
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841242
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750