DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30486 and CRISPLD1

DIOPT Version :9

Sequence 1:	NP_725234.2	Gene:	CG30486 / 246645	FlyBaseID:	FBgn0050486	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_113649.1	Gene:	CRISPLD1 / 83690	HGNCID:	18206	Length:	500	Species:	Homo sapiens

Alignment Length:	212	Identity:	48/212 - (22%)
Similarity:	72/212 - (33%)	Gaps:	67/212 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 DFRNTVAKGQYPHLRPASRMATLRWHEELAGLAKFALRRCDYIDDYCSNTDEFSYVSYIYGSTKW 134
            |..|.:....||   .||.|..:.|..||...|:.....|                       .|
Human    67 DLHNKLRSQVYP---TASNMEYMTWDVELERSAESWAESC-----------------------LW 105

  Fly   135 LQLEKDPISVL-----------------DFVLQFWMDDVKGCTMAHINAEKPAKDGQCRG----Y 178
               |..|.|:|                 .|.:|.|.|:||..:..:.:...|....:|.|    :
Human   106 ---EHGPASLLPSIGQNLGAHWGRYRPPTFHVQSWYDEVKDFSYPYEHECNPYCPFRCSGPVCTH 167

  Fly   179 FTQLVQDLAAHVGCAMMLRK-----GQ--TSGLYQYGVLCHFS-RGKIANELVYRASAHPGSRC- 234
            :||:|...:..:|||:.|..     ||  ...:|   ::|::| :|.......|: ...|.|.|
Human   168 YTQVVWATSNRIGCAINLCHNMNIWGQIWPKAVY---LVCNYSPKGNWWGHAPYK-HGRPCSACP 228

  Fly   235 --YAGTHSIYEGLCSPE 249
              :.|  ...|.||..|
Human   229 PSFGG--GCRENLCYKE 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30486	NP_725234.2	SCP_euk	61..214	CDD:240180	37/171 (22%)
CRISPLD1	NP_113649.1	SCP_euk	63..207	CDD:240180	37/171 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..281
		LCCL	291..375	CDD:128866
		LCCL	392..483	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151165
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750