DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30486 and CLEC18B

DIOPT Version :9

Sequence 1:	NP_725234.2	Gene:	CG30486 / 246645	FlyBaseID:	FBgn0050486	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001011880.2	Gene:	CLEC18B / 497190	HGNCID:	33849	Length:	455	Species:	Homo sapiens

Alignment Length:	253	Identity:	59/253 - (23%)
Similarity:	89/253 - (35%)	Gaps:	69/253 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 RAHLLAVLNDFRNTVAKGQYP------------------------HLR-------PASRMATLRW 94
            |.||||||.....|.....:|                        |.|       ||:.|..|.|
Human    10 RGHLLAVLLALLGTTWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRSWVQPPAADMRRLDW 74

  Fly    95 HEELAGLAKFALRRCDYIDDYCSNTDEFSYVSYIYGSTKWLQ----LEKDPISVLDF--VLQFWM 153
            .:.||.||:.....|.           ....|...|..:.||    ::..|..:..|  |:..|.
Human    75 SDSLAQLAQARAALCG-----------IPTPSLASGLWRTLQVGWNMQLLPAGLASFVEVVSLWF 128

  Fly   154 DDVKGCTMAHINAEKPAKDGQCRGYFTQLVQDLAAHVGCAMML-RKGQTSGLYQYGVLCHFSRG- 216
              .:|...:|. |.:.|::..|. ::||||...::.:||...| ..|||:   ....:|.:|.|
Human   129 --AEGQRYSHA-AGECARNATCT-HYTQLVWATSSQLGCGRHLCSAGQTA---IEAFVCAYSPGG 186

  Fly   217 --KIANELV--YRASAHPGSRCYAGTHSIYE------GLCS-PEEHVNPNALQLGELN 263
              ::..:.:  |:..|. .|.|.|.....::      |||. |......:....|.||
Human   187 NWEVNGKTIIPYKKGAW-CSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLN 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30486	NP_725234.2	SCP_euk	61..214	CDD:240180	45/190 (24%)
CLEC18B	NP_001011880.2	SCP_euk	50..183	CDD:240180	36/150 (24%)
CLEC18B	NP_001011880.2	CLECT	310..443	CDD:153057
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151056
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840