DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30486 and vap-2

DIOPT Version :9

Sequence 1:	NP_725234.2	Gene:	CG30486 / 246645	FlyBaseID:	FBgn0050486	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	258	Identity:	53/258 - (20%)
Similarity:	89/258 - (34%)	Gaps:	75/258 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ISQEALSTDYCNKDLCLPEITHIACRNYGDFDESCGSEAIIMKFPMHMRAHLLAVLNDFRNTVAK 77
            :..|.|:...|||.    .||.:             .:.||           |...|:.|.::|.
Worm    85 LDDELLTEHVCNKS----TITQL-------------QQEII-----------LTTHNELRRSLAF 121

  Fly    78 GQYPHLR----PASRMATLRWHEELAGLAKFALRRC--DYIDDYC--SNTDEFS-YVSYIYGSTK 133
            |:..:.|    .|..|..|.|..|||.||......|  .::....  ||...|. :..|..|...
Worm   122 GKQRNKRGLMNGARNMYKLDWDCELASLAANWSTSCPQHFMPQSVLGSNAQLFKRFYFYFDGHDS 186

  Fly   134 WLQLEKDPISVLDFVLQFW--MDDVKGCTMAHINAEKPAKDGQCRGYF--TQLVQDLAAHVGCAM 194
            .:.:..        .:::|  ..:.||      |.::..:....|.||  ..:.:.....|||:.
Worm   187 TVHMRN--------AMKYWWQQGEEKG------NEDQKNRFYARRNYFGWANMAKGKTYRVGCSY 237

  Fly   195 MLRKGQTSGLYQYGVLCHFS-RGKIANELVYR----------ASAHPGSRCYAGTHSIYEGLC 246
            ::.....|.|:    .|.:: :.:...|::|.          ...:|||:|.     :.||||
Worm   238 IMCGDGESALF----TCLYNEKAQCEKEMIYENGKPCCEDKDCFTYPGSKCL-----VPEGLC 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30486	NP_725234.2	SCP_euk	61..214	CDD:240180	34/165 (21%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553	36/177 (20%)
vap-2	NP_001300377.1	SCP	315..468	CDD:214553
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820