DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ave and SAMD15

DIOPT Version :9

Sequence 1:	NP_725413.1	Gene:	ave / 246638	FlyBaseID:	FBgn0050476	Length:	106	Species:	Drosophila melanogaster
Sequence 2:	NP_001010860.1	Gene:	SAMD15 / 161394	HGNCID:	18631	Length:	674	Species:	Homo sapiens

Alignment Length:	112	Identity:	31/112 - (27%)
Similarity:	56/112 - (50%)	Gaps:	12/112 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EETINSTQNKTRTKTTRPKAVYL-WTVSDVLKWYRRHCGEYTQYEQLFAQHDITGRALLRITDSS 66
            :|.::........|.|..:..:| |...:|.:|..: .| :.||::.|..:.|:||.|:.:..|:
Human   521 KERVSEDDETQPEKGTELQFEHLNWDPEEVAEWISQ-LG-FPQYKECFITNFISGRKLIHVNCSN 583

  Fly    67 LQRMGVTDNRDREAIWR------EIVKQRLKTDI-MEIRDMERLNIY 106
            |.:||:|:..|.:||.|      ||.:...|..| :..||:  :.:|
Human   584 LPQMGITNFEDMKAISRHTQELLEIEEPLFKRSISLPYRDI--IGLY 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ave	NP_725413.1	SAM_aveugle-like	21..94	CDD:188909	24/79 (30%)
SAMD15	NP_001010860.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..448
		ftsN	137..>310	CDD:274041
		SAM_Samd14	543..609	CDD:188929	22/67 (33%)
		SAM	544..607	CDD:197735	20/64 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910