DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant9 and galnt14

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	XP_021324149.1	Gene:	galnt14 / 562739	ZFINID:	ZDB-GENE-041014-351	Length:	573	Species:	Danio rerio

Alignment Length:	559	Identity:	218/559 - (38%)
Similarity:	302/559 - (54%)	Gaps:	65/559 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 EQPKKKPQEDSKKVIDPPA------------------NFEENPGELGKPVRLPKEMSDEMKKAVD 168
            |||:.|....:..::|...                  .|||.           ..:|....|...
Zfish    39 EQPQVKEAYAASSMVDTNCWQQRINTISDTEWDDLLEEFEEK-----------SYLSAHRWKPGQ 92

  Fly   169 DGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVL 233
            |.::..||||..|:.|..:|.|.|.|...| ....|..:||.|.::|.|||||.:.|||||.|||
Zfish    93 DPYSLYAFNQRESERIPSNRALRDTRHYRC-TTLHYDPDLPSTTIVITFHNEARSTLLRTVRSVL 156

  Fly   234 DRSPEHLIGKIILVDDYSDMPH---LKRQLEDYFAAYPKVQIIRGQKREGLIRARILGANHAKSP 295
            :|:|.|||.:||||||:|:.|:   |..:|       |||:.:|.:.||||||:|:.||:.|.:.
Zfish   157 NRTPVHLIHEIILVDDFSEDPNDCLLLTKL-------PKVKCLRNKHREGLIRSRVRGADAAGAQ 214

  Fly   296 VLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWNLQFS 360
            :||:||||||..:.||.|||.|:..:.|:|..||||:|:.:|..|....|.  ..|||||:|.|.
Zfish   215 ILTFLDSHCEVNKDWLPPLLQRVKEDPTSVASPVIDIINMDTFAYVAASSD--LRGGFDWSLHFK 277

  Fly   361 WHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGG 425
            |..:...:|.:.....||:.:|.:|||||.|||.:|:|||.||:..|||||||.|:||:.|||||
Zfish   278 WEQLSAEKRAKRADPTEPIKTPIIAGGLFVIDRSWFNRLGKYDTAMDIWGGENFEISFRVWMCGG 342

  Fly   426 TLEIVPCSHVGHIFRKRSPYKWRSG-VNVLKKNSVRLAEVWMDEYSQYYYHRIGNDKG-DWGDVS 488
            :|||:|||.|||:|||:.||.:..| .|...||:.|.|||||||:..:||......:| .:||:.
Zfish   343 SLEIIPCSRVGHVFRKKHPYIFPEGNANTYIKNTRRTAEVWMDEFKLFYYSARPAARGKSYGDIH 407

  Fly   489 DRRKLRNDLKCKSFKWYLDNIYPELFIPGDSVA-HGEIRNLGYGGRTCLDAPAGKKHQKKAVGTY 552
            .|::||..|.||||||||||:||||.:|.||.| .|.||.    .:.||::...:......:...
Zfish   408 GRQELRKSLNCKSFKWYLDNVYPELKVPDDSDAKSGVIRQ----RQNCLESRVVEGQDLPVLTLA 468

  Fly   553 PC----HRQGGNQYWMLSKAGEIRRDDSCLD----YAGKDVTLFGCHGGKGNQFWTYRENTKQLH 609
            ||    .....||.|:.:...:||:...||.    :....:.|..|:...|.|.|  :::...|.
Zfish   469 PCIITKETPAANQEWIYTHGQQIRQQQYCLSVSTTFPASQILLMPCNISDGKQRW--QKSGTHLE 531

  Fly   610 HGTSGKC----LAIS--ESKDKLLMEECSASLSRQQWTL 642
            |..|..|    :|:.  ||...|::..|..|...|:|.:
Zfish   532 HLASRFCVDSEMALDGIESSKMLVISPCELSAHTQRWEM 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	139/274 (51%)
		pp-GalNAc-T	213..510	CDD:133004	153/301 (51%)
		Ricin_B_lectin	521..640	CDD:279046	31/133 (23%)
		RICIN	523..642	CDD:238092	31/132 (23%)
galnt14	XP_021324149.1	pp-GalNAc-T	135..429	CDD:133004	153/302 (51%)
galnt14	XP_021324149.1	Ricin_B_lectin	442..568	CDD:306998	30/131 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586961
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750