DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant9 and galnt1

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	XP_009290644.1	Gene:	galnt1 / 559073	ZFINID:	ZDB-GENE-030131-2360	Length:	557	Species:	Danio rerio

Alignment Length:	531	Identity:	258/531 - (48%)
Similarity:	339/531 - (63%)	Gaps:	32/531 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 DSKK---------VIDPPANFEENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISV 186
            |.||         |:..|   .:.|||:||||.:.|:..::||:.    :..|.||...|::|::
Zfish    35 DDKKERGLPGRDTVVQRP---HDGPGEMGKPVVIAKDQQEKMKEM----FKINQFNLMASEMIAL 92

  Fly   187 HRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYS 251
            :|:|||.|...||.:. |..:||:|.|:|.|||||||.||||||||:||||.||:.:|:||||.|
Zfish    93 NRSLPDVRLEGCKTKV-YPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDAS 156

  Fly   252 DMPHLKRQLEDYFAAYP-KVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLL 315
            :...||||||.|..... .|:::|.::|.||||||:.||:.:...|:|:||:|||||.|||||||
Zfish   157 ERDFLKRQLEHYVRKLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLL 221

  Fly   316 DRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWNLQFSWHPVPERER-KRHNSTAEPV 379
            .||..:..|||||:||||||:|.|  |.....:..|||:|.|.|.|:|||:||. :|......||
Zfish   222 SRIKLDKKTVVCPIIDVISDDTFE--YMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPV 284

  Fly   380 YSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSP 444
            .:||||||||||||::|..:||||:|.|||||||||:||:.|.||||||||.||||||:|||.:|
Zfish   285 RTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATP 349

  Fly   445 YKWRSGV-NVLKKNSVRLAEVWMDEYSQYYY-HRIGNDKGDWGDVSDRRKLRNDLKCKSFKWYLD 507
            |.:..|. .::.||:.|||||||||:..::| ...|..|.|:||:|.|..||..|:||.|.|||:
Zfish   350 YTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRTSLRQRLQCKPFSWYLE 414

  Fly   508 NIYPELFIPGDSVAHGEIRNLGYGGRTCLDAPAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIR 572
            |:||:..||....:.|||||:  ....|||..|.|:::|  ||.:.||..||||.:..:...|||
Zfish   415 NVYPDSQIPRHYYSLGEIRNV--ETNQCLDNMARKENEK--VGIFNCHGMGGNQVFSYTANKEIR 475

  Fly   573 RDDSCLDYA--GKDVTLFGCHGGKGNQFWTYRENTKQLHHGTSGKCLAISESKDKLL--MEECSA 633
            .||.|||.:  ...|.:..||..||||.|.|......|.|..|.:||..:...|..:  :.:||.
Zfish   476 TDDLCLDVSKLNGPVMMLKCHHLKGNQLWEYDPVKLSLVHVNSNQCLDKASEDDSQVPSVRDCSG 540

  Fly   634 SLSRQQWTLEN 644
            :.| |||.|.|
Zfish   541 ARS-QQWLLRN 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	159/274 (58%)
		pp-GalNAc-T	213..510	CDD:133004	173/300 (58%)
		Ricin_B_lectin	521..640	CDD:279046	46/122 (38%)
		RICIN	523..642	CDD:238092	48/122 (39%)
galnt1	XP_009290644.1	pp-GalNAc-T	117..417	CDD:133004	173/301 (57%)
		RICIN	430..548	CDD:238092	48/122 (39%)
		Ricin_B_lectin	430..546	CDD:279046	46/120 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52215
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102903
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.730