DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant9 and galnt7

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	NP_001018477.1	Gene:	galnt7 / 553668	ZFINID:	ZDB-GENE-050522-284	Length:	652	Species:	Danio rerio

Alignment Length:	643	Identity:	228/643 - (35%)
Similarity:	329/643 - (51%)	Gaps:	99/643 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 AGEDFGINGNVIGGGGQKQAHDEADIPPTVGKHKAD---------------LQAERMRKKAAEQP 124
            ||:|     |...|...::| |:...|.....:.||               :..|.:|:|..:.|
Zfish    32 AGDD-----NPFAGVMAREA-DKLPQPNLPNNNVADQFKPVVPWPHVEGVEVDLESIRQKNVDNP 90

  Fly   125 ----KKKPQED--SKKVI----------DPP------ANFEE----------NPGELGKPVRLPK 157
                |.:.|::  .|:.|          ||.      .|||.          .|||..||..|..
Zfish    91 NPAFKAQNQQNVIQKQYITFKPHTNMYSDPVLNKGTLGNFEPKEPEPHGVQGGPGEGSKPFVLGP 155

  Fly   158 EMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCK----DEARYLTNLPKTDVIICFH 218
            |..|.::.::.:    ..||...||:||:.||:.|.|...||    ||     ||..:.|||.||
Zfish   156 EYKDAVQASIKE----FGFNMVASDMISLDRTVGDLRHEECKYWNYDE-----NLLTSSVIIVFH 211

  Fly   219 NEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAY-PKVQIIRGQKREGLI 282
            ||.|:.|:||||||:.|:|...:.:|:::||:|:..|||.:||:|...: ..|::.|.:||||||
Zfish   212 NEGWSTLMRTVHSVIKRTPRKYLAEIVMIDDFSNKAHLKERLEEYIKQWNGLVKVFRNEKREGLI 276

  Fly   283 RARILGANHAK-SPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVI--SDETLE-YHYR 343
            :||.:||..|. ..||.|||:|||....|..||:..|:::.|....|:||.|  :|.|:| ....
Zfish   277 QARSIGARKATLGKVLIYLDAHCEVGVNWYAPLVAPISKDRTVCTVPLIDYIDGNDYTIEPQQGG 341

  Fly   344 DSGGVNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDI 408
            |..|:..|.:||:|.:...|:..||:.:.....||..||.||||||:|:||||..||.||.|..|
Zfish   342 DEDGLARGAWDWSLLWKRVPLSSREKAKRKHKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQI 406

  Fly   409 WGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRS-------GVNVLKKNSVRLAEVWM 466
            |||||.|:|:|.|.|||.|..||||.||||:|.:.   |:.       |.:...||.||:.|||.
Zfish   407 WGGENFEISYKIWQCGGQLLFVPCSRVGHIYRLQG---WQGNPPPAHVGSSPTLKNYVRVVEVWW 468

  Fly   467 DEYSQYYY-HRIGNDKGDWGDVSDRRKLRNDLKCKSFKWYLDNI-------YPELFIPGDSVAHG 523
            |:|..|:| .|.......:||:|..:|.|.:.:||||||:::.|       ||   :|..:|..|
Zfish   469 DDYKDYFYASRPETLTLAYGDISTLKKFREEHRCKSFKWFMEEIAYDIPLHYP---LPPKNVEWG 530

  Fly   524 EIRNLGYGGRTCLDAPAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIRRDDSCLDYA--GKDVT 586
            |||  ||....|:|:..........:|  ||||.||||.:.:::|.::.:.|.||...  |..|.
Zfish   531 EIR--GYETSYCIDSMGHTNGGNVEIG--PCHRMGGNQLFRINEANQLMQYDQCLTKGGDGSAVI 591

  Fly   587 LFGCHGGKGNQFWTYRENTKQLHHGTSGKCLAISESKDKLLMEECSASLSRQQWTLEN 644
            :..|:..:..: |.|.::..:..|..:||||..|:...|:.:.:|..|.|.|:|.:.|
Zfish   592 ITHCNLNEHTE-WKYFKDLHRFTHVPTGKCLDRSDVLHKVYIADCDNSKSSQKWEMNN 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	128/283 (45%)
		pp-GalNAc-T	213..510	CDD:133004	138/316 (44%)
		Ricin_B_lectin	521..640	CDD:279046	37/120 (31%)
		RICIN	523..642	CDD:238092	38/120 (32%)
galnt7	NP_001018477.1	pp-GalNAc-T	205..513	CDD:133004	137/310 (44%)
		BcsA	205..>433	CDD:224136	107/227 (47%)
		Ricin_B_lectin	529..644	CDD:279046	37/119 (31%)
		RICIN	530..646	CDD:238092	38/120 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586944
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850