DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant9 and Galntl5

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	NP_001020319.1	Gene:	Galntl5 / 499968	RGDID:	1565271	Length:	443	Species:	Rattus norvegicus

Alignment Length:	372	Identity:	166/372 - (44%)
Similarity:	227/372 - (61%)	Gaps:	23/372 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 GWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLD 234
            |.::...|...|..:.:.|.:||.|:..|: :..|..|||...|||||:||.:..|||||.||::
  Rat    82 GLSRYGLNVITSRRLGIERQVPDSRNKICQ-QKHYPFNLPTASVIICFYNEEFNTLLRTVSSVMN 145

  Fly   235 RSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAY-PKVQIIRGQKREGLIRARILGANHAKSPVLT 298
            .||:||:.:||||||.|:...||.:|:.:...: .|::::|.:|||||||:|::||:.|...:|.
  Rat   146 LSPKHLLEEIILVDDMSEFDDLKAKLDYHLEIFRGKIKLVRNKKREGLIRSRMIGASRASGDILV 210

  Fly   299 YLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNV-GGFDWNLQFSWH 362
            :||||||....||||||..||::...|||||||||.:.||:|    .|...| |.|||||.|.|.
  Rat   211 FLDSHCEVNRVWLEPLLHAIAKDHKMVVCPVIDVIDELTLDY----VGSPIVRGAFDWNLNFRWD 271

  Fly   363 PVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTL 427
            .|...|.......:.|:.||.|:||:|:|:|.:|:.||.||...|:|||||:|||.:.|||||.|
  Rat   272 DVFSYELDGPEGPSTPIRSPAMSGGIFAINRHYFNELGQYDKDMDLWGGENVELSLRIWMCGGQL 336

  Fly   428 EIVPCSHVGHIFRKRSPYKWRSGVN--VLKKNSVRLAEVWMDEYSQ-YYYHRIGNDKGDWGDVSD 489
            .|:|||.|||..:..|..:.   ||  .|.||.:|:..||:|||.: ::..|........|::||
  Rat   337 FILPCSRVGHNNKALSKNRL---VNQSALSKNLLRVVHVWLDEYKENFFLQRPSLTHVSCGNISD 398

  Fly   490 RRKLRNDLKCKSFKWYLDNIYPELFIPGDSVAHGEIRNLGYGGRTCL 536
            |.:||..|.||||:||||||:|||          |..|.|.|.:..|
  Rat   399 RVELRKRLGCKSFQWYLDNIFPEL----------EPLNRGKGTKPFL 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	132/275 (48%)
		pp-GalNAc-T	213..510	CDD:133004	145/301 (48%)
		Ricin_B_lectin	521..640	CDD:279046	5/16 (31%)
		RICIN	523..642	CDD:238092	5/14 (36%)
Galntl5	NP_001020319.1	pp-GalNAc-T	123..419	CDD:133004	145/302 (48%)
Galntl5	NP_001020319.1	Glyco_tranf_2_3	123..355	CDD:290369	117/235 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345976
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750