Protein Alignment Pgant9 and GALNT18

DIOPT Version :9

• Sequence 1: NP_001097342.1
• Gene: Pgant9 / 246627
• FlyBaseID: FBgn0050463
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_940918.2
• Gene: GALNT18 / 374378
• HGNCID: 30488
• Length: 607
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 183/569 - (32%)
• Similarity: 292/569 - (51%)
• Gaps: 64/569 - (11%)

  Fly   124 PKKKPQE---DSKKVI---------------DPPANFEENPGELGKPVRL----PKEMSDEMKKA 166
            |.||.:|   |:.|:|               :.||..||...|......|    .:|:|.|.::.
Human    48 PDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRV 112

  Fly   167 VDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHS 231
            ....:....:|.|:||.:.:.|.|||.|.:.|:: ..:..:||:..::..|.|||.:||||::||
Human   113 ALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRN-LSFPDSLPEVSIVFIFVNEALSVLLRSIHS 176

  Fly   232 VLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPK-----VQIIRGQKREGLIRARILGANH 291
            .::|:|.||:.:||||||.|....||.:|.:|......     ::::|..|:|||||:|:.|...
Human   177 AMERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNSQKPGFIKVVRHSKQEGLIRSRVSGWRA 241

  Fly   292 AKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWN 356
            |.:||:...|:|.|...||.||:|.||..|...::.|..|.|..:..|.   :...:...||||.
Human   242 ATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEI---EEYPLAAQGFDWE 303

  Fly   357 LQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTW 421
            |...:...|:...|..|||| |:.||.:. |.|.:||::|..:|..|.|.:::||||:||..:.|
Human   304 LWCRYLNPPKAWWKLENSTA-PIRSPALI-GCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVW 366

  Fly   422 MCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWMDEYSQYYYHRIG---NDKG- 482
            .|||::|::|||.:.||.|...||......:| ::|::|:|||||||:..:.|....   .|.|
Human   367 QCGGSVEVLPCSRIAHIERAHKPYTEDLTAHV-RRNALRVAEVWMDEFKSHVYMAWNIPQEDSGI 430

  Fly   483 DWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDSVAHGEIRNLGYGGRTCLDAPAGKKHQKK 547
            |.||::.|:.||..|:||:|:|||.::|||:.:..|.:|:|.::| ......|||  .|...:..
Human   431 DIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQN-SLKTDLCLD--QGPDTENV 492

  Fly   548 AVGTYPCH-RQGGNQYWMLSK-------AGEIRRDDS-CLDYAGKDVTLFGCHGGKGNQF---WT 600
            .: .|.|| ....|.|:..|:       :..:..||: ||........|..|...|..:.   |.
Human   493 PI-MYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQ 556

  Fly   601 YRENTKQLHHGTSGKCLAISESKD-----KLLMEECSASLSRQQWTLEN 644
            :.:. ..:.:..|.:||.:.|:.|     :|::::||.    |.|::.|
Human   557 FSQG-GPIQNRKSKRCLELQENSDLEFGFQLVLQKCSG----QHWSITN 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	106/275 (39%)
		pp-GalNAc-T	213..510	CDD:133004	119/305 (39%)
		Ricin_B_lectin	521..640	CDD:279046	30/135 (22%)
		RICIN	523..642	CDD:238092	30/135 (22%)
GALNT18	NP_940918.2	Catalytic subdomain A	153..267		47/113 (42%)
		pp-GalNAc-T	157..458	CDD:133004	119/306 (39%)
		Catalytic subdomain B	324..385		27/61 (44%)
		RICIN	471..598	CDD:238092	30/135 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152464
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740