DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant9 and Galnt14

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	NP_001012109.1	Gene:	Galnt14 / 313878	RGDID:	1310068	Length:	552	Species:	Rattus norvegicus

Alignment Length:	545	Identity:	218/545 - (40%)
Similarity:	309/545 - (56%)	Gaps:	56/545 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 SKKVIDPPANFEENPGELGKPVRLPK----------EMSDEMK-------KAVDDGWTKNAFNQY 179
            :|:.::.|         ||..|:.||          |..||.:       :..||.:...||||.
  Rat    27 TKRKLEVP---------LGPEVQTPKPSDADWDDLWEQFDERRYLNAKKWRVGDDPYKLYAFNQR 82

  Fly   180 VSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKI 244
            .|:.||.:|.:||.|...| ....|.|:||.|.:||.|||||.:.||||:.|||:|:|.|||.:|
  Rat    83 ESERISSNRAVPDTRHKRC-SLLVYCTDLPPTSIIITFHNEARSTLLRTIRSVLNRTPMHLIQEI 146

  Fly   245 ILVDDYSDMPHLKRQLEDYFAAYPKVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEG 309
            |||||:|:.|...:||    ...|||:.:|..:|:||:|:|:.||:.|:...||:||||||....
  Rat   147 ILVDDFSNDPEDCKQL----IKLPKVKCLRNSERQGLVRSRMRGADIAQGTTLTFLDSHCEVNRD 207

  Fly   310 WLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWNLQFSWHPVPERERKRHNS 374
            ||:|||.|:..:.|.|||||||:|:.:|  ::|.:|.....|||||:|.|.|..:...::.....
  Rat   208 WLQPLLHRVKEDYTRVVCPVIDIINLDT--FNYIESASELRGGFDWSLHFQWEQLSVEQKALRLD 270

  Fly   375 TAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIF 439
            ..||:.:|.:|||||.||:.:||.||.||...|||||||.|:||:.|||||.|||:|||.|||:|
  Rat   271 PTEPIRTPIIAGGLFVIDKAWFDYLGKYDVDMDIWGGENFEISFRVWMCGGGLEIIPCSRVGHVF 335

  Fly   440 RKRSPYKWRSG-VNVLKKNSVRLAEVWMDEYSQYYY-HRIGNDKGDWGDVSDRRKLRNDLKCKSF 502
            ||:.||.:..| .|...||:.|.||||||||.|||| .|....:..:|::.:|..||.:|.|::|
  Rat   336 RKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYAARPFALERPFGNIENRLNLRKNLHCQTF 400

  Fly   503 KWYLDNIYPELFIPGD-SVAHGEIRNLGYGGRTCLDAPAGKKHQKKAVGTYPCHRQGG----NQY 562
            ||||:|:||||.:|.| |:..|.||.    .:.||::...|..:...:...||.:..|    :|.
  Rat   401 KWYLENVYPELRVPPDSSIQKGNIRQ----RQKCLESQKQKNQETPHLRLSPCAKVKGDRAKSQV 461

  Fly   563 WMLSKAGEIRRDDSCLD----YAGKDVTLFGCHGGKGNQFWTYRENTKQLHHGTSGKCLAI---- 619
            |..:...:|.:::.||.    :.|..|.|..|..|...|.||  :...::.|..|..||..
  Rat   462 WAFTYTQQIIQEELCLSVVTLFPGAPVVLVLCKNGDERQQWT--KTGARIEHIASHLCLDTDMFG 524

  Fly   620 --SESKDKLLMEECSASLSRQQWTL 642
              :|...::::..|.:||..|.|.:
  Rat   525 DSTEDGKEVVVNPCESSLMSQHWDI 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	141/272 (52%)
		pp-GalNAc-T	213..510	CDD:133004	150/298 (50%)
		Ricin_B_lectin	521..640	CDD:279046	31/132 (23%)
		RICIN	523..642	CDD:238092	32/132 (24%)
Galnt14	NP_001012109.1	Glyco_tranf_2_3	111..337	CDD:290369	118/231 (51%)
		pp-GalNAc-T	114..408	CDD:133004	150/299 (50%)
		RICIN	422..549	CDD:238092	32/132 (24%)
		Ricin_B_lectin	422..547	CDD:279046	31/130 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345978
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750