DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant9 and Galnt9

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	NP_001116116.1	Gene:	Galnt9 / 304571	RGDID:	1311523	Length:	604	Species:	Rattus norvegicus

Alignment Length:	540	Identity:	191/540 - (35%)
Similarity:	287/540 - (53%)	Gaps:	59/540 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 PANFEENPGELGK---PVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKD 200
            |....|.||.||:   ...|..:..:...|..|.|     :|..:||.||:.||:||.|...|:
  Rat    85 PIGLVEGPGGLGQGGVAATLQDDSQETEGKFEDFG-----YNAQLSDRISLDRTIPDYRPKRCR- 143

  Fly   201 EARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDY-F 264
            :..|..:||:..|:..|.|||.:|:||:||||::.:|..|:.:||||||.||...||..|:.| .
  Rat   144 QITYSEDLPQISVVFIFVNEALSVILRSVHSVVNHTPSQLLKEIILVDDNSDNVELKFNLDQYVH 208

  Fly   265 AAYP-KVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCP 328
            ..|| .|:::|..:||||||||:.|...|.:|::.:.|:|.|...||.||.|.||..:...::.|
  Rat   209 KRYPGLVKVVRNSRREGLIRARLQGWKVATAPIVGFFDAHVEFNTGWAEPALARIQEDRRRIILP 273

  Fly   329 VIDVISDETLEYHYRDSGGVNVGGFDWNLQFSW--HPVPERERKRHNSTAEPVYSPTMAGGLFSI 391
            .||.|...|.|.....|.   ..|::|.|   |  :.:|.::.......:.|:.:|.|.|..|.:
  Rat   274 AIDNIKYSTFEVQQYASA---AHGYNWGL---WCMYIIPPQDWLDRGDESAPIRTPAMIGCSFVV 332

  Fly   392 DREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGVN-VLK 455
            |||:|..:|..|.|.:::|.||:||..:.|.|||::|::|||.|.||.|.:.||  .:.:: ..|
  Rat   333 DREYFGDIGLLDPGMEVYGAENIELGMRVWQCGGSMEVLPCSRVAHIERTKKPY--NNDIDYYAK 395

  Fly   456 KNSVRLAEVWMDEYSQYYYHR----IGNDKGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIP 516
            :|::|.||||||::..:.|..    :.|...|:||||:|..||..|||:||||||:|:|||:.|.
  Rat   396 RNALRAAEVWMDDFKSHVYMAWNIPMTNPGVDFGDVSERLALRQKLKCRSFKWYLENVYPEMRIY 460

  Fly   517 GDSVAHGEIRN---LGYGGRTCLDAPAGKKHQKKAVGTYPCH-------RQGGNQYWMLSKAGE- 570
            .:::.:||:||   .||    |||  .|.:...:|: .||||       |...:....|...|.
  Rat   461 NNTLTYGEVRNSKASGY----CLD--QGAEDDDRAI-LYPCHGMSSQLVRYSADGLLQLGPLGST 518

  Fly   571 -IRRDDSCL--DYAGKDVTLFGCH--GGKGNQFWTYRENTKQLHHGTSGKCLAISESKD-----K 625
             ...|..||  |..|:..||..|.  .....:.|.:.::...:...| |:||.:..|||     :
  Rat   519 AFLPDSKCLVDDGRGRMPTLKKCEDVARPTQRLWDFTQSGPIVSRDT-GRCLEVEMSKDANFGLR 582

  Fly   626 LLMEECSASLSRQQWTLENY 645
            |:::.||.    |:|.:.|:
  Rat   583 LVVQRCSG----QKWMIRNW 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	106/279 (38%)
		pp-GalNAc-T	213..510	CDD:133004	123/305 (40%)
		Ricin_B_lectin	521..640	CDD:279046	38/139 (27%)
		RICIN	523..642	CDD:238092	39/139 (28%)
Galnt9	NP_001116116.1	pp-GalNAc-T	155..454	CDD:133004	123/306 (40%)
		Ricin_B_lectin	465..593	CDD:279046	38/139 (27%)
		RICIN	467..595	CDD:238092	39/139 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740