DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant9 and Galnt17

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	NP_660253.2	Gene:	Galnt17 / 212996	MGIID:	2137594	Length:	598	Species:	Mus musculus

Alignment Length:	528	Identity:	198/528 - (37%)
Similarity:	286/528 - (54%)	Gaps:	48/528 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 ENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNL 208
            |..|..||. .||..:|...::.......|..:|.|:|:.||:.|::||.|...|| |.:|...|
Mouse    89 EGYGGRGKG-GLPATLSPSEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCK-ELKYSKEL 151

  Fly   209 PKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDY-FAAYP-KVQ 271
            |:..:|..|.|||.:|:||:|||.::.:|.||:.:||||||.||...||..||:| ...|| .|:
Mouse   152 PQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKAPLEEYVHKRYPGLVK 216

  Fly   272 IIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDE 336
            ::|.|||||||||||.|...|...|..:.|:|.|.|.||.||:|.||..|...|:.|.||.|..:
Mouse   217 VVRNQKREGLIRARIEGWKAATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQD 281

  Fly   337 TLE-YHYRDSGGVNVGGFDWNLQFSW--HPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDR 398
            ..| ..|.:|    ..|:.|.|   |  :..|.::.......:.|:.:|.|.|..|.::|:||..
Mouse   282 NFEVQRYENS----AHGYSWEL---WCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGE 339

  Fly   399 LGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAE 463
            :|..|.|.|::||||:||..|.|:|||::|::|||.|.||.||:.||....|. ..|:|::|:||
Mouse   340 IGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGF-YTKRNALRVAE 403

  Fly   464 VWMDEYSQYYYHR----IGNDKGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDSVAHGE 524
            ||||:|..:.|..    :.|...|.||||:|:.||..||||:|:||||::|||:....:::|:||
Mouse   404 VWMDDYKSHVYIAWNLPLENPGIDIGDVSERKALRKSLKCKNFQWYLDHVYPEMRRYNNTIAYGE 468

  Fly   525 IRNLGYGGRTCLDAPAGKKHQKKAVGTYPCHRQGGNQYWMLSKAG----------EIRRDDSCLD 579
            :|| ......|||  .|......|: .|||| ..|.|....:|.|          .:..|..||.
Mouse   469 LRN-NKAKDVCLD--QGPLENHTAI-LYPCH-GWGPQLARYTKEGFLHLGALGTTTLLPDTRCLV 528

  Fly   580 YAGKD--VTLFGCHGGKGNQF--WTYRENTKQLHHGTSGKCLAISESKD----KLLMEECSASLS 636
            ...|.  ..|..|...|.:.:  |.:.:|...::.|| |:||.: |::.    .|::..|:.
Mouse   529 DNSKSRLPQLLDCDKVKSSLYKRWNFIQNGAIMNKGT-GRCLEV-ENRGLAGIDLILRSCTG--- 588

  Fly   637 RQQWTLEN 644
             |:|.::|
Mouse   589 -QRWAIKN 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	118/279 (42%)
		pp-GalNAc-T	213..510	CDD:133004	134/305 (44%)
		Ricin_B_lectin	521..640	CDD:279046	36/136 (26%)
		RICIN	523..642	CDD:238092	36/136 (26%)
Galnt17	NP_660253.2	Catalytic subdomain A	151..262		56/110 (51%)
		pp-GalNAc-T	155..454	CDD:133004	134/306 (44%)
		Catalytic subdomain B	319..381		30/61 (49%)
		RICIN	467..593	CDD:238092	36/136 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740