DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant9 and Galnt10

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	XP_038941033.1	Gene:	Galnt10 / 170501	RGDID:	69409	Length:	752	Species:	Rattus norvegicus

Alignment Length:	708	Identity:	280/708 - (39%)
Similarity:	372/708 - (52%)	Gaps:	118/708 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RRRSTTIVKLVAFALA---------IWFCIAFLVYTDDTRRRAAQEGAGASGAGSAPGVGGGAGG 61
            ||:...:::.||.|||         :|     .:|    |.|......|.|||..||....|...
  Rat    94 RRKEKRLLQAVALALAALVLLPNVGLW-----ALY----RERQPDGSPGGSGAAVAPEAIQGWFS 149

  Fly    62 LGDPIALALRNEPAGEDFGINGNVIGGGGQKQAH---------------------DEADIPPTVG 105
            ......|.|...|.               :.||.                     |..|: |:..
  Rat   150 SCRAWELLLTFPPQ---------------ESQAQLLLQSQELWLWTQASPGRHLLDTLDL-PSYT 198

  Fly   106 KHKADLQAERMRKK---AAEQ------PKKKPQEDSKKVIDPPANFEENPGELGKPVRLPKEMSD 161
            :..|:|.: |.:|.   .|||      .|:..:.|:::|         ..||.|||.    .|:|
  Rat   199 ESVAELHS-RQKKTLFLGAEQRLKDWHNKEAIRRDAQRV---------GNGEQGKPY----PMTD 249

  Fly   162 EMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLL 226
              .:.||..:.:|.||.||||.||::|:|||.|...|..:. ||..||.|.:||.||||.|:.||
  Rat   250 --AERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKL-YLETLPNTSIIIPFHNEGWSSLL 311

  Fly   227 RTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPKVQIIRGQKREGLIRARILGANH 291
            |||||||:|||..|:.:|:||||:||..|||:.||||.|.:|.|:|:|.:|||||||.|:|||:.
  Rat   312 RTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIRTRMLGASA 376

  Fly   292 AKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWN 356
            |...|:|:||||||....||.|||||||||..|:|||:||||..:...|. ..:|....|.|||.
  Rat   377 ATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYE-TQAGDAMRGAFDWE 440

  Fly   357 LQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTW 421
            :.:...|:|...:|...|  :|..||.||||||::||::|..||.||.|.:|||||..|:|||.|
  Rat   441 MYYKRIPIPPELQKADPS--DPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVW 503

  Fly   422 MCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWMDEYSQYYYHRIGNDKGDW-- 484
            ||||.:|.:|||.||||:||..|||..:||: |.:|..|:||||||||::|.|.|    :.::
  Rat   504 MCGGRMEDIPCSRVGHIYRKYVPYKVPAGVS-LARNLKRVAEVWMDEYAEYIYQR----RPEYRH 563

  Fly   485 ---GDVSDRRKLRNDLKCKSFKWYLDNI---YPELFIPGD--SVAHGEIRNLGYGGRTCLDAPAG 541
               |||..::|||..|.||||||::..|   .|:.:.|.:  :.|.|||||:|.|  .|.|...|
  Rat   564 LSAGDVVAQKKLRGSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTG--LCTDTKHG 626

  Fly   542 KKHQKKAVGTYPCHRQGGNQYW------MLSKAGEIRRDDS------CLDYAG--KDVTLFGCHG 592
            .......:.|  |.|..|...|      ..:...:||..|.      |.|...  ..|||:.||.
  Rat   627 TLGSPLRLET--CIRGRGEAAWNSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHS 689

  Fly   593 GKGNQFWTYRENTKQLHHGTSGKCLAISESKDKLLMEECSASLSRQQWTLENYDSSKL 650
            .||||.|.||:: |.|:|..||.|:..|||..::.|..|:.|...|||..|:.:|:.|
  Rat   690 MKGNQLWKYRKD-KTLYHPVSGSCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNSTVL 746

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	151/270 (56%)
		pp-GalNAc-T	213..510	CDD:133004	162/304 (53%)
		Ricin_B_lectin	521..640	CDD:279046	46/132 (35%)
		RICIN	523..642	CDD:238092	47/132 (36%)
Galnt10	XP_038941033.1	pp-GalNAc-T	297..592	CDD:133004	161/302 (53%)
Galnt10	XP_038941033.1	Ricin_B_lectin	608..736	CDD:395527	46/132 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345973
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740