DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pgant9 and GALNT5

DIOPT Version :9

Sequence 1:NP_001097342.1 Gene:Pgant9 / 246627 FlyBaseID:FBgn0050463 Length:650 Species:Drosophila melanogaster
Sequence 2:XP_016858726.1 Gene:GALNT5 / 11227 HGNCID:4127 Length:956 Species:Homo sapiens


Alignment Length:601 Identity:228/601 - (37%)
Similarity:322/601 - (53%) Gaps:102/601 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    93 QAHDEADIPPTVGKHKADLQAERMRKKAAEQPKKKPQEDSKKVIDPPANFEENPGELGKPVRLP- 156
            |:|.:|.:|...|.|:.      :|......|:           ||.|     ||:.|:||.:| 
Human   407 QSHIKALLPEDSGTHQV------LRIDVTLSPR-----------DPKA-----PGQFGRPVVVPH 449

  Fly   157 -KEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNE 220
             ||...|.:      |.:..||.|:||||.|.|.:.|.|.|.|.::..: .|||.|.||:||.:|
Human   450 GKEKEAERR------WKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVH-NNLPTTSVIMCFVDE 507

  Fly   221 AWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPKVQIIRGQKREGLIRAR 285
            .|:.|||:||||::|||.|||.:|:||||:|...:||..|:.|.:.:|||:|:|.::|.||||||
Human   508 VWSTLLRSVHSVINRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFPKVRILRLKERHGLIRAR 572

  Fly   286 ILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNV 350
            :.||.:|...|||:||||.||..|||||||:|:..:...|.||||:||:|:.:.|...|:  ...
Human   573 LAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDN--FQR 635

  Fly   351 GGFDWNLQFSWHPVP----ERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGG 411
            |.|.|.:.|.|..:|    .:.|.:...|   :..|.|||||||||:.:|..|||||.|.|:|||
Human   636 GIFVWPMNFGWRTIPPDVIAKNRIKETDT---IRCPVMAGGLFSIDKSYFFELGTYDPGLDVWGG 697

  Fly   412 ENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKW-RSGVNVLKKNSVRLAEVWMDEYSQYYY- 474
            ||:|||||.|||||.:||:|||.||||||..:||.: :..:..:::|.||:||||:|||.:.:| 
Human   698 ENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDEYKELFYG 762

  Fly   475 ---HRIGNDKG-DWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDSVAHGEIRNLGYGGRTC 535
               |.|  |:| |.|:::.:|:||..||||||||||:|::|:|..| ...|.|.:.|:..|  .|
Human   763 HGDHLI--DQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLRAP-IVRASGVLINVALG--KC 822

  Fly   536 L----------DAPAGKKHQ----------------------KKAVGTYPCHRQGGNQYWMLSKA 568
            :          |....|:.|                      |.||..:||..:.....|:....
Human   823 ISIENTTVILEDCDGSKELQQFNYTWLRLIKCGEWCIAPIPDKGAVRLHPCDNRNKGLKWLHKST 887

  Fly   569 G----EIRRDDSCLDYAGKDVTLFGCHGGKGNQFWTYRENTKQLHHGTSGKCLAISESKDKLLME 629
            .    |:..:.:|..:... ::|...|        ...||.:||      .||..:.|:..|.:.
Human   888 SVFHPELLSNSACGSFPAL-LSLQVNH--------IVFENNQQL------LCLEGNFSQKILKVA 937

  Fly   630 ECSASLSRQQWTLENY 645
            .|......|:|..|.|
Human   938 ACDPVKPYQKWKFEKY 953

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pgant9NP_001097342.1 WcaA 207..>478 CDD:223539 141/279 (51%)
pp-GalNAc-T 213..510 CDD:133004 156/306 (51%)
Ricin_B_lectin 521..640 CDD:279046 28/154 (18%)
RICIN 523..642 CDD:238092 28/154 (18%)
GALNT5XP_016858726.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165152456
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3736
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D606683at2759
OrthoFinder 1 1.000 - - FOG0002384
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11675
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
76.810

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