Protein Alignment Pgant9 and POC1B-GALNT4

DIOPT Version :9

• Sequence 1: NP_001097342.1
• Gene: Pgant9 / 246627
• FlyBaseID: FBgn0050463
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_001186710.1
• Gene: POC1B-GALNT4 / 100528030
• HGNCID: 42957
• Length: 575
• Species: Homo sapiens
• Alignment Length: 597
• Identity: 252/597 - (42%)
• Similarity: 342/597 - (57%)
• Gaps: 78/597 - (13%)

  Fly    78 DFGINGNVIGGGGQKQAHDEADIPPTVGKHK-ADLQAERMRKKAAEQPKKKPQEDSKKVIDPPAN 141
            |...||..:|.|..::          :|..: :|||  :..:..:....|||..||:.:
Human    25 DLSPNGKQLGAGRARE----------LGSRRLSDLQ--KNTEDLSRPLYKKPPADSRAL------ 71

  Fly   142 FEENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLT 206
                 ||.||..:|  :::::..|..::...:.|.|.|:||.||:||.:.|.|...||.:.....
Human    72 -----GEWGKASKL--QLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNYR 129

  Fly   207 NLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPKVQ 271
            .||.|.|||.|:||||:.||||:||||:.||..|:.:||||||.||..:||.|||.|.:...:|:
Human   130 TLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVYLKTQLETYISNLDRVR 194

  Fly   272 IIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDE 336
            :||..|||||:|||::||..|...|||:||.||||..|||||||:||.|:.|.|||||||.|...
Human   195 LIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWN 259

  Fly   337 TLEYHYRDSGGVNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGT 401
            |.|: |...|...:|||||.|.|.||.||::||.|..|..:|:.|||||||||::.:::|..|||
Human   260 TFEF-YMQIGEPMIGGFDWRLTFQWHSVPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQYLGT 323

  Fly   402 YDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWM 466
            ||:|.::||||||||||:.|.|||.|||.|||||||:|.||:||   :..|.| :|:.|.|||||
Human   324 YDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPY---ARPNFL-QNTARAAEVWM 384

  Fly   467 DEYSQYYYHRIGND---KGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDSVA-HGEIRN 527
            |||.:::|:|  |.   |..:||:|:|:.||..|:||||.|||.|::|.|.:|.|... ||.||:
Human   385 DEYKEHFYNR--NPPARKEAYGDISERKLLRERLRCKSFDWYLKNVFPNLHVPEDRPGWHGAIRS 447

  Fly   528 LGYGGRTCLD------APAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIRRD---DSCLD---- 579
            .|.... |||      .|.|..     :..:.||.|||||::..:...|||.:   :.|.:
Human   448 RGISSE-CLDYNSPDNNPTGAN-----LSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPEQ 506

  Fly   580 --YAG-----KDVTLFGCHGG---KGNQFWTYRENTKQLHHGTSGKCLA---ISESKDKLLMEEC 631
              |.|     ||        |   ..|..|.::|: ..:.|..||.||:   ..|.:..:.|..|
Human   507 KNYVGMQNCPKD--------GFPVPANIIWHFKED-GTIFHPHSGLCLSAYRTPEGRPDVQMRTC 562

  Fly   632 SASLSRQQWTLE 643
            .|....|.|:.|
Human   563 DALDKNQIWSFE 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	157/270 (58%)
		pp-GalNAc-T	213..510	CDD:133004	171/299 (57%)
		Ricin_B_lectin	521..640	CDD:279046	39/145 (27%)
		RICIN	523..642	CDD:238092	39/144 (27%)
POC1B-GALNT4	NP_001186710.1	WcaA	131..427	CDD:223539	173/302 (57%)
		pp-GalNAc-T	135..429	CDD:133004	171/300 (57%)
		RICIN	443..573	CDD:238092	39/144 (27%)
		Ricin_B_lectin	443..571	CDD:279046	38/142 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152453
Domainoid	1	1.000	223	1.000	Domainoid score	I2581
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740