Protein Alignment Pgant9 and POC1B-GALNT4

DIOPT Version :10

• Sequence 1: NP_725602.1
• Gene: Pgant9 / 246627
• FlyBaseID: FBgn0050463
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_001186710.1
• Gene: POC1B-GALNT4 / 100528030
• HGNCID: 42957
• Length: 575
• Species: Homo sapiens
• Alignment Length: 597
• Identity: 252/597 - (42%)
• Similarity: 342/597 - (57%)
• Gaps: 78/597 - (13%)

  Fly    78 DFGINGNVIGGGGQKQAHDEADIPPTVGKHK-ADLQAERMRKKAAEQPKKKPQEDSKKVIDPPAN 141
            |...||..:|.|..::          :|..: :|||  :..:..:....|||..||:.:
Human    25 DLSPNGKQLGAGRARE----------LGSRRLSDLQ--KNTEDLSRPLYKKPPADSRAL------ 71

  Fly   142 FEENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLT 206
                 ||.||..:|  :::::..|..::...:.|.|.|:||.||:||.:.|.|...||.:.....
Human    72 -----GEWGKASKL--QLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNYR 129

  Fly   207 NLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPKVQ 271
            .||.|.|||.|:||||:.||||:||||:.||..|:.:||||||.||..:||.|||.|.:...:|:
Human   130 TLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVYLKTQLETYISNLDRVR 194

  Fly   272 IIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDE 336
            :||..|||||:|||::||..|...|||:||.||||..|||||||:||.|:.|.|||||||.|...
Human   195 LIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWN 259

  Fly   337 TLEYHYRDSGGVNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGT 401
            |.|: |...|...:|||||.|.|.||.||::||.|..|..:|:.|||||||||::.:::|..|||
Human   260 TFEF-YMQIGEPMIGGFDWRLTFQWHSVPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQYLGT 323

  Fly   402 YDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWM 466
            ||:|.::||||||||||:.|.|||.|||.|||||||:|.||:||   :..|.| :|:.|.|||||
Human   324 YDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPY---ARPNFL-QNTARAAEVWM 384

  Fly   467 DEYSQYYYHRIGND---KGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDSVA-HGEIRN 527
            |||.:::|:|  |.   |..:||:|:|:.||..|:||||.|||.|::|.|.:|.|... ||.||:
Human   385 DEYKEHFYNR--NPPARKEAYGDISERKLLRERLRCKSFDWYLKNVFPNLHVPEDRPGWHGAIRS 447

  Fly   528 LGYGGRTCLD------APAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIRRD---DSCLD---- 579
            .|.... |||      .|.|..     :..:.||.|||||::..:...|||.:   :.|.:
Human   448 RGISSE-CLDYNSPDNNPTGAN-----LSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPEQ 506

  Fly   580 --YAG-----KDVTLFGCHGG---KGNQFWTYRENTKQLHHGTSGKCLA---ISESKDKLLMEEC 631
              |.|     ||        |   ..|..|.::|: ..:.|..||.||:   ..|.:..:.|..|
Human   507 KNYVGMQNCPKD--------GFPVPANIIWHFKED-GTIFHPHSGLCLSAYRTPEGRPDVQMRTC 562

  Fly   632 SASLSRQQWTLE 643
            .|....|.|:.|
Human   563 DALDKNQIWSFE 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_725602.1	tolA	<91..>134	CDD:236545	9/43 (21%)
		pp-GalNAc-T	213..510	CDD:133004	171/299 (57%)
		beta-trefoil_Ricin_Pgant9-like	518..643	CDD:467340	41/151 (27%)
POC1B-GALNT4	NP_001186710.1	pp-GalNAc-T	135..429	CDD:133004	171/300 (57%)
		beta-trefoil_Ricin_GALNT4	439..574	CDD:467347	40/149 (27%)