DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant9 and galnt15

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	XP_002932836.2	Gene:	galnt15 / 100489899	XenbaseID:	XB-GENE-982198	Length:	613	Species:	Xenopus tropicalis

Alignment Length:	565	Identity:	199/565 - (35%)
Similarity:	292/565 - (51%)	Gaps:	41/565 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 GGGQKQAHDEADIPPTVGKHKADLQAERMR-----KKAAEQPKKKPQEDSKKVI---DPPANFEE 144
            |||...|.:             ||..||..     |.....|....:|:....|   .|..||::
Frog    52 GGGHGWAGE-------------DLVQERAEESNHFKVELLSPLSSLREEGLIAIGMSGPERNFDK 103

  Fly   145 NPGELGKPVRLPKEMSDEMKKA--VDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTN 207
            .|.::.:.|:..|..::|...:  :......|.|::.||..|.:||.:||.|...|..: .|...
Frog   104 VPRKMYRIVKQLKRKNEETSPSLVLRSELNTNGFDEEVSKNIPLHRIIPDGRHPECLQQ-NYGEK 167

  Fly   208 LPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPKVQI 272
            ||...||||||||.|:.||||||||||.||...:.:||||||.|...|||..|.:|.:....|::
Frog   168 LPIASVIICFHNEGWSTLLRTVHSVLDNSPRTFLKEIILVDDLSHQEHLKSALSEYISRIGGVKL 232

  Fly   273 IRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDET 337
            ||..||.|:|..|:|||..|...||.::||||||..|||||||.||..|...:|.||||.|..:|
Frog   233 IRSNKRLGVIGGRMLGAARATGEVLIFMDSHCECHPGWLEPLLSRIMHNRNRIVSPVIDFIDWKT 297

  Fly   338 LEYHYRDSGGVNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTY 402
            .||.:  |..:..|.|||.|.|.|.|:||.|.|...|...|..||.:.|.:.:.||.:|..:|.:
Frog   298 FEYSH--SSLLQQGVFDWKLDFHWVPLPEHEEKVRQSPIIPFRSPVIPGYVLASDRHYFQNIGGF 360

  Fly   403 DSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWMD 467
            |:|.:.||.|..|||.:.|:|||::||||||.|||.::..:.:......:|| ::.||.||:|||
Frog   361 DTGINSWGVETTELSIRVWLCGGSVEIVPCSRVGHAYQNHTMHNSVQNEDVL-RSKVRTAELWMD 424

  Fly   468 EYSQYYYHRIGN---DKGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDSV-AHGEIRNL 528
            .|...:|..:||   ::....|:::..:||..|.||.|:|:|.|:|||:.:...:: :.|::.|.
Frog   425 SYKAIFYRNVGNSLLNRIQESDINEHEQLRQRLGCKRFQWFLANVYPEINMSTSTLESSGQLFNA 489

  Fly   529 GYGGRTCLDAPAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIRRDD--SCLDYAGKDVTLFGCH 591
            |:|  .|:.....::.....|....|. :.|||.:..:...|||...  .||....:.::...|.
Frog   490 GFG--LCMTHTFRERLFVTPVKLSSCD-ENGNQVFEYNSVNEIRLTSVPLCLTVRHEQISFENCT 551

  Fly   592 GGK--GNQFWTYRENTKQLHHGTSGKCLAI--SESKDKLLMEECS 632
            ..|  .::.|.:.: ...:.|..:|||:..  :.::..|.:..||
Frog   552 TSKPAASRLWHFGQ-AGSITHIPTGKCIEAMGTGARKSLYLNPCS 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	128/270 (47%)
		pp-GalNAc-T	213..510	CDD:133004	138/299 (46%)
		Ricin_B_lectin	521..640	CDD:279046	25/118 (21%)
		RICIN	523..642	CDD:238092	25/116 (22%)
galnt15	XP_002932836.2	pp-GalNAc-T	172..470	CDD:133004	138/300 (46%)
galnt15	XP_002932836.2	Ricin_B_lectin	482..602	CDD:395527	25/118 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	1	1.000	-	-		FOG0002384
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010