DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant9 and galnt6.2

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	XP_031753046.1	Gene:	galnt6.2 / 100486937	XenbaseID:	XB-GENE-1000674	Length:	623	Species:	Xenopus tropicalis

Alignment Length:	669	Identity:	247/669 - (36%)
Similarity:	356/669 - (53%)	Gaps:	86/669 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RRSTTIVKLVAFALAIWFCIAFLVYTDDTRRRAAQEGAGASGAGSAPGVGGGAGGLGDPIALALR 71
            ||:...:||....: ::....|:::.|                     :|.||  ..||   .::
Frog     5 RRNYGPLKLAMVGM-VFVIFVFIMHKD---------------------IGNGA--KDDP---WIK 42

  Fly    72 NEPAGEDFGINGNVIGGGGQKQAHDEADIPPTVGKHKADLQAERMRKKAAEQPKK------KPQE 130
            |....:|..||   :..|..|...|  .||      |..:.|.....:..|:.|.      .|.|
Frog    43 NIVVRKDQMIN---MMRGAMKNLKD--SIP------KLQIMAPVQEVRPVEEKKSCLPGYYTPAE 96

  Fly   131 DSKKVIDPPANFEENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTL-PDPR 194
             .|..::.|.....:||..||.. :....::|..:..:.|:.|:.||.:.||.||:||.| ||.|
Frog    97 -LKPFMERPPQDPNSPGADGKGF-IKNIWTEEEVEEKEKGFDKHCFNAFASDRISLHRALGPDTR 159

  Fly   195 DAWC-KDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKR 258
            ...| :.:.:...:||.|.:||.||||||:.|||||:|||..||..|:.:||||||.|:..:||.
Frog   160 PLECIEQKFKRCPSLPTTSIIIVFHNEAWSTLLRTVYSVLYTSPAILLKEIILVDDASEDEYLKE 224

  Fly   259 QLEDYFAAYPKVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNST 323
            :|:||..|...|:|.|.::|:|||.||:|||:.|...|||:||:||||..|||||||.|:|.:.|
Frog   225 KLDDYVKALQIVKIARQKERKGLITARLLGASIATGEVLTFLDAHCECFHGWLEPLLSRVAEDHT 289

  Fly   324 TVVCPVIDVISDETLEYHYR-DSGGVNV-GGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAG 386
            .||.|.|..|:..|.|:... ..|.:|. |.|||:|.|:|..:|..:.|:......|:.:||.||
Frog   290 AVVSPDITAINYNTFEFGKPVQQGKMNSRGNFDWSLAFNWEAIPAADEKQRKDETYPIKTPTFAG 354

  Fly   387 GLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGV 451
            |||||.:.:|:.:|:||...:||||||:|:||:.|.|||.|||:|||.|||:||.:||:.:..|.
Frog   355 GLFSISKAYFEHIGSYDEEMEIWGGENVEMSFRVWQCGGKLEIIPCSVVGHVFRTKSPHTFPKGT 419

  Fly   452 NVLKKNSVRLAEVWMDEYSQYYYHR------IGNDKGDWGDVSDRRKLRNDLKCKSFKWYLDNIY 510
            .|:.:|.|||||||||:|...||.|      |..:| .:||:|.|.||:.||:||:|.|||:|||
Frog   420 QVILRNQVRLAEVWMDDYKVLYYRRNEQAAKIAKEK-SFGDISKRLKLKADLQCKNFTWYLENIY 483

  Fly   511 PELFIPG-DSVAHGEIRNLGYGGRTCLDAPAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIR-- 572
            ||:|:|. |...:|.|:|  .|.:.|:|......:..:....||||..|||||:..|...|:|
Frog   484 PEMFVPDRDPTYYGAIKN--EGTQNCIDVGENNNYGSQLPIMYPCHGMGGNQYFEYSTHKELRHN 546

  Fly   573 -RDDSCL--------------DYAGKDVTLFGCHGGKGNQFWTYRENTKQLHHGTSGKCLAISES 622
             :...||              .|.|::.|:      .||:.|.:.:: :.:.:..|..||  :..
Frog   547 LKTQLCLCSKYEPGPVKLVDCQYKGQNTTV------PGNEEWEFTKD-RLIRNVGSNMCL--TAQ 602

  Fly   623 KDKLLMEECSASLSRQQWT 641
            .|.....||:.....|.|:
Frog   603 GDHPSTAECNPDDIDQLWS 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	141/278 (51%)
		pp-GalNAc-T	213..510	CDD:133004	155/304 (51%)
		Ricin_B_lectin	521..640	CDD:279046	33/135 (24%)
		RICIN	523..642	CDD:238092	34/136 (25%)
galnt6.2	XP_031753046.1	OppC_N	1..>27	CDD:403960	5/22 (23%)
		pp-GalNAc-T	178..483	CDD:133004	155/305 (51%)
		Ricin_B_lectin	496..620	CDD:395527	33/134 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910