Protein Alignment Pgant9 and galnt12

DIOPT Version :10

• Sequence 1: NP_725602.1
• Gene: Pgant9 / 246627
• FlyBaseID: FBgn0050463
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: XP_002935181.2
• Gene: galnt12 / 100485011
• XenbaseID: XB-GENE-986239
• Length: 597
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 251/584 - (42%)
• Similarity: 356/584 - (60%)
• Gaps: 49/584 - (8%)

  Fly    83 GNVIGGGGQKQAHDEADIPPTVGKHKAD-LQA-ERMRKKAAEQPKKKPQEDSKKVIDPPANFEEN 145
            |.::.|||:          |..||:..| ::| |.:..:..:.| .:..||.:::..|.  :|:.
 Frog    31 GFLLMGGGE----------PDSGKNLVDEVEAVEHLEPRDVDDP-GEDAEDYEQLRKPV--YEKP 82

  Fly   146 P------GELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARY 204
            |      ||.|:.|||  .:|.:.|:..::...|:..|.|:||.||:||.|.:..:..||.....
 Frog    83 PLDPNVLGEFGRAVRL--NLSGKEKELENESIHKHQINIYLSDKISLHRRLEERWNPMCKTVKYK 145

  Fly   205 LTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPK 269
            ...||||.|||.|:||||:.|||||||||:.||:.|:.:|||||||||..|||..||.|.:::.|
 Frog   146 YRRLPKTSVIIAFYNEAWSTLLRTVHSVLETSPDLLLEEIILVDDYSDREHLKEPLEKYISSWRK 210

  Fly   270 VQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVIS 334
            |::||..|||||:|||:|||:.||:.|||:||.||||.||||||||:||....:.|:|||||||.
 Frog   211 VRLIRANKREGLVRARLLGASIAKAEVLTFLDCHCECHEGWLEPLLERIREKESAVICPVIDVID 275

  Fly   335 DETLEYHYRDSGGVNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRL 399
            ..|.|| ..::|...:|||||.:.|:||.|||.|:|:..|..:.:.||||||||||:.:::|:.|
 Frog   276 WNTFEY-LGNAGEPQIGGFDWRMVFTWHTVPETEQKKRRSPIDVISSPTMAGGLFSVSKKYFEHL 339

  Fly   400 GTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEV 464
            |:||:|.::|||||||.||:.|.|||:||:.|||||||:|.:::||.....::    ||||.|||
 Frog   340 GSYDTGMEVWGGENLEFSFRIWQCGGSLEVHPCSHVGHVFPRQAPYSRSKALS----NSVRAAEV 400

  Fly   465 WMDEYSQYYYHRIGN-DKGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDSVAH-GEIRN 527
            |:|||.:.||||..: .|..:||||:|.:|:..|:||.|||:||||||||.:|.|.... |.::|
 Frog   401 WLDEYKEIYYHRNPHARKEPYGDVSERLQLKERLQCKHFKWFLDNIYPELHVPEDKPGRFGMLKN 465

  Fly   528 LGYGGRTCLD--APAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEI----RRDDSC--LDYAGKD 584
            .|. ...|.|  .|.......:.:..||||..|.||::..:...||    |:.:.|  .|:....
 Frog   466 KGM-ENVCFDYNPPNENDVSGQQIILYPCHGMGQNQFFEYTSYNEIRYNTRQPEGCASADFDSDH 529

  Fly   585 VTLFGC-HGGK---GNQFWTYRENTKQLHHGTSGKCLA----ISESKDKLLMEECSASLSRQQW 640
            :|:|.| ..|:   .||.:.:|:: ..|.|..:.||:.    |.....:.::..||.| ..|:|
 Frog   530 LTMFLCRENGQEVPENQKFIFRDD-GILFHPKTKKCVQAVRNIKNEDPEPVLRPCSES-DNQKW 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_725602.1	tolA	<91..>134	CDD:236545	9/44 (20%)
		pp-GalNAc-T	213..510	CDD:133004	169/297 (57%)
		beta-trefoil_Ricin_Pgant9-like	518..643	CDD:467340	36/140 (26%)
galnt12	XP_002935181.2	pp-GalNAc-T	153..447	CDD:133004	169/298 (57%)
		beta-trefoil_Ricin_GALNT12	457..596	CDD:467349	35/138 (25%)