DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant9 and Galnt6

DIOPT Version :9

Sequence 1:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	NP_001165534.1	Gene:	Galnt6 / 100361647	RGDID:	2319726	Length:	622	Species:	Rattus norvegicus

Alignment Length:	562	Identity:	230/562 - (40%)
Similarity:	320/562 - (56%)	Gaps:	59/562 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 AEQPKKKPQEDSKKVI-------------DPPANFEENPGELGKPVRLPKEMSDEMKKAVDDGWT 172
            |.:|::.|...:...:             :.|.....:||..||..: .||.:....:..|:|:.
  Rat    75 APEPQQNPVSTNHSCLPGFYTPAELRPFWERPPQDPNSPGADGKAFQ-KKEWTLLETQEKDEGYK 138

  Fly   173 KNAFNQYVSDLISVHRTL-PDPRDAWCKDEA-RYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDR 235
            |:.||.:.||.||:.|:| ||.|...|.|:. |....||.|.|:|.||||||:.|||||:|||..
  Rat   139 KHCFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPLPTTSVVIVFHNEAWSTLLRTVYSVLHT 203

  Fly   236 SPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPKVQIIRGQKREGLIRARILGANHAKSPVLTYL 300
            ||..|:.:||||||.|...|||.:||.|......|:::|.|:|:|||.||:|||:.|::.|||:|
  Rat   204 SPAILLKEIILVDDASTDEHLKEKLERYVQQLQIVRVVRQQERKGLITARLLGASVAQAEVLTFL 268

  Fly   301 DSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEY---------HYRDSGGVNVGGFDWN 356
            |:||||..|||||||.|||.:.|.||.|.|..|...|.::         |.|       |.|||:
  Rat   269 DAHCECFHGWLEPLLARIAEDKTAVVSPDIVTIDLNTFQFSKPMRRGKAHSR-------GNFDWS 326

  Fly   357 LQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTW 421
            |.|.|..:||.|::|......|:.|||.|||||||.:.:|:.:||||:..:||||||:|:||:.|
  Rat   327 LTFGWEMLPEHEKQRRKDETYPIKSPTFAGGLFSISKAYFEHIGTYDNQMEIWGGENVEMSFRVW 391

  Fly   422 MCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWMDEYSQYYYHRIGN------- 479
            .|||.|||:|||.|||:||.:||:.:..|.:|:.:|.|||||||||:|.:.:|.|  |
  Rat   392 QCGGQLEIIPCSVVGHVFRTKSPHTFPKGTSVIARNQVRLAEVWMDDYKKIFYRR--NLQAAKMA 454

  Fly   480 DKGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPG-DSVAHGEIRNLGYGGRTCLDAPAGKK 543
            .:.::||||:|.:||..|.|.:|.|||.|:|||:|:|. :....|.|:|||..  .|||.....:
  Rat   455 KENNFGDVSERLRLREQLHCHNFSWYLHNVYPEMFVPDLNPTFSGAIKNLGTS--QCLDVGENNR 517

  Fly   544 HQKKAVGTYPCHRQGGNQYWMLSKAGEIRRD---DSCLDYAGKDVTLFGCHG-GKGNQF-----W 599
            ..|..: .|.||..|||||:..:...::|.:   ..||..:|..:.|..|.. ||.::.     |
  Rat   518 GGKPLI-MYVCHNLGGNQYFEYTSQRDLRHNIGKQLCLHASGSTLGLRNCQFIGKNSEVPKDEEW 581

  Fly   600 TYRENTKQLHHGTSGKCLAISESKDKL-LMEECSASLSRQQW 640
            ...:: :.:.:..||.||.   ||||. .|..|:.|...|.|
  Rat   582 ELTQD-QLIRNLGSGTCLT---SKDKKPAMAPCNPSDPYQLW 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	144/279 (52%)
		pp-GalNAc-T	213..510	CDD:133004	156/312 (50%)
		Ricin_B_lectin	521..640	CDD:279046	38/128 (30%)
		RICIN	523..642	CDD:238092	39/128 (30%)
Galnt6	NP_001165534.1	pp-GalNAc-T	180..485	CDD:133004	156/313 (50%)
Galnt6	NP_001165534.1	Ricin_B_lectin	497..619	CDD:395527	38/128 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345969
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850