Protein Alignment Tdc2 and DPL1

DIOPT Version :9

• Sequence 1: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_010580.1
• Gene: DPL1 / 851888
• SGDID: S000002702
• Length: 589
• Species: Saccharomyces cerevisiae
• Alignment Length: 513
• Identity: 96/513 - (18%)
• Similarity: 176/513 - (34%)
• Gaps: 155/513 - (30%)

  Fly    20 YLETLNERRVT---PSVEPGYLR---HLLP-PEAPQEPEDWDQIMRDV-------------EDKI 64
            :|....|:.||   .|:|...:|   .|:. |:.|......|.::.::             |.|:
Yeast   105 FLRGTVEKEVTKVKQSIEDELIRSDSQLMNFPQLPSNGIPQDDVIEELNKLNDLIPHTQWKEGKV 169

  Fly    65 MPGV-------THWQHPRFHAYFPAGNSFPSILGDMLGDGIGCIGFSWAASPACTELETIVLDWL 122
            ...|       .|.|...:..|..|....|.:.                  ||..::|:.|:..:
Yeast   170 SGAVYHGGDDLIHLQTIAYEKYCVANQLHPDVF------------------PAVRKMESEVVSMV 216

  Fly   123 GKAIGLPDHFLALKEGSTGGGVIQTSASECVLVTMLAARAQALKRLKAQHPFVEEGHLLSKLMAY 187
            .:....|        ..||.|...:..:|.:|:..|:|:..||     .|..:.|..:::.:
Yeast   217 LRMFNAP--------SDTGCGTTTSGGTESLLLACLSAKMYAL-----HHRGITEPEIIAPV--- 265

  Fly   188 CSKEAHSCVEKAAMICFVKLRILEPDDDASLRGQTIYEAMEEDELQGLVPFFVSTTLGTTGSC-- 250
               .||:..:|||....:|||.:|.|       .|.|:.    :|..:..|....|:...||.
Yeast   266 ---TAHAGFDKAAYYFGMKLRHVELD-------PTTYQV----DLGKVKKFINKNTILLVGSAPN 316

  Fly   251 ----AFDNLPEIGKQLQRFPGVWLHVDAAYAGNSFICPELK-------PLLKGIEYADSFNTNPN 304
                ..|::..:||..|::. :.||||:..  .|||...::       |||       .|.. |.
Yeast   317 FPHGIADDIEGLGKIAQKYK-LPLHVDSCL--GSFIVSFMEKAGYKNLPLL-------DFRV-PG 370

  Fly   305 KWLLTNFDCSTLWVRDRIRLTSALVVDPLYLKHGYS---DAAIDYRH------------------ 348
               :|:..|.|                   .|:|::   .:.|.||:
Yeast   371 ---VTSISCDT-------------------HKYGFAPKGSSVIMYRNSDLRMHQYYVNPAWTGGL 413

  Fly   349 WGVPLSRRFRS----LKLWFVLRSYGISGLQHYIRHHIKLAKRFEELVLKD-KRFEICNQVKLGL 408
            :|.|.....|.    :..|..:.:.|.:|.....:..:..|.:|::.:.:: ....|....:..:
Yeast   414 YGSPTLAGSRPGAIVVGCWATMVNMGENGYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSV 478

  Fly   409 VCFRLKG------SDKLNEK--LLSIINESGKLHMVPASVGDRYIIRFCAVAQNATAE 458
            :.|..|.      ||:|::|  ..:.:.:...|||....:....:...|.:.:....|
Yeast   479 ISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAHVVDEICDILRTTVQE 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:278699	80/441 (18%)
DPL1	NP_010580.1	GadA	106..543	CDD:223154	96/512 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810